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The Future of SARS-CoV-2 Vaccination - Lessons from Influenza

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Article Medicine, General & Internal

BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting

Noa Dagan et al.

Summary: A study conducted in Israel on nearly 600,000 individuals showed that the BNT162b2 mRNA vaccine was effective in reducing the risk of infection, hospitalization, and severe Covid-19. The effectiveness in preventing death was 72% during the period from day 14 through day 20 after the first dose, and hospitalization was reduced by 87% for the period 7 or more days after the second dose, similar to results from a randomized trial.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Immunology

Coronavirus Occurrence in the Household Influenza Vaccine Evaluation (HIVE) Cohort of Michigan Households: Reinfection Frequency and Serologic Responses to Seasonal and Severe Acute Respiratory Syndrome Coronaviruses

Joshua G. Petrie et al.

Summary: Reinfection with seasonal HCoVs is frequent, and binding anti-spike protein antibodies do not correlate with protection from seasonal HCoV infection, with little cross-response to SARS-CoV-2 proteins.

JOURNAL OF INFECTIOUS DISEASES (2021)

Article Multidisciplinary Sciences

Overdispersion in COVID-19 increases the effectiveness of limiting nonrepetitive contacts for transmission control

Kim Sneppen et al.

Summary: The overdispersion of COVID-19 transmission gives the virus a weakness: reducing contacts between people who do not regularly meet would significantly reduce the pandemic, while reducing repeated contacts in defined social groups would be less effective.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)