期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 28, 期 11, 页码 875-+出版社
NATURE PORTFOLIO
DOI: 10.1038/s41594-021-00675-6
关键词
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The online and interactive G-protein coupled receptor (GPCR) structure analysis platform allows any researcher to analyze and visualize a plethora of structure-function relationships across the scales of atomic interactions to protein backbone rearrangements.
We present an online, interactive platform for comparative analysis of all available G-protein coupled receptor (GPCR) structures while correlating to functional data. The comprehensive platform encompasses structure similarity, secondary structure, protein backbone packing and movement, residue-residue contact networks, amino acid properties and prospective design of experimental mutagenesis studies. This lets any researcher tap the potential of sophisticated structural analyses enabling a plethora of basic and applied receptor research studies. An online and interactive G-protein coupled receptor (GPCR) structure analysis platform allows any researcher to analyze and visualize a plethora of structure-function relationships across the scales of atomic interactions to protein backbone rearrangements.
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