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Refining oxytocin therapy for autism: context is key

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NATURE REVIEWS NEUROLOGY
卷 18, 期 2, 页码 67-68

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NATURE PORTFOLIO
DOI: 10.1038/s41582-021-00602-9

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  1. NIH [P50MH100023, R01MH112788, P51OD011132]

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The recent clinical trial showed that chronic intranasal oxytocin does not have a direct impact on social behavior in children with autism spectrum disorders. Future trials should combine oxytocin with behavioral therapy to enhance learning and improve social behavior.
A recent clinical trial found no effect of chronic intranasal oxytocin on social behaviour in children with autism spectrum disorders. The result is not surprising, as oxytocin facilitates social learning but does not directly cause prosocial behaviour. In future trials, oxytocin should be paired with behavioural therapy to enhance learning and improve social behaviour.

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