4.6 Review

Health inequities and the inappropriate use of race in nephrology

期刊

NATURE REVIEWS NEPHROLOGY
卷 18, 期 2, 页码 84-94

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NATURE PORTFOLIO
DOI: 10.1038/s41581-021-00501-8

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  1. NIH [K23DK114526, U54MD000214, K02AG059140, R01AG054363, R25HL126145, P30AG059298, UL1TR001881, P30AG021684]

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The authors discuss how structural racism contributes to health disparities in minority racial groups and analyze the impact of using race coefficients in estimating glomerular filtration rate on health inequities in Black patients with kidney disease. Concerns have been raised regarding the use of race in assessing kidney disease, with emphasis on the role of race and racism in medicine. It is important to recognize and address the nuances of racism in healthcare to avoid perpetuating historical racist concepts that exacerbate health inequities in marginalized populations.
Here, the authors discuss how structural racism underlies many of the health disparities that affect individuals from minority racial groups. They also examine how the use of race coefficients in estimated glomerular filtration rate equations might contribute to health inequities in Black patients with kidney disease. Chronic kidney disease is an important clinical condition beset with racial and ethnic disparities that are associated with social inequities. Many medical schools and health centres across the USA have raised concerns about the use of race - a socio-political construct that mediates the effect of structural racism - as a fixed, measurable biological variable in the assessment of kidney disease. We discuss the role of race and racism in medicine and outline many of the concerns that have been raised by the medical and social justice communities regarding the use of race in estimated glomerular filtration rate equations, including its relationship with structural racism and racial inequities. Although race can be used to identify populations who experience racism and subsequent differential treatment, ignoring the biological and social heterogeneity within any racial group and inferring innate individual-level attributes is methodologically flawed. Therefore, although more accurate measures for estimating kidney function are under investigation, we support the use of biomarkers for determining estimated glomerular filtration rate without adjustments for race. Clinicians have a duty to recognize and elucidate the nuances of racism and its effects on health and disease. Otherwise, we risk perpetuating historical racist concepts in medicine that exacerbate health inequities and impact marginalized patient populations.

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