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COVID-19 vaccination in kidney transplant recipients

NATURE REVIEWS NEPHROLOGY (2021)

The ROMANOV study found impaired humoral and cellular immune responses to SARS-CoV-2 mRNA vaccine in virus-unexposed patients receiving maintenance hemodialysis

Maxime Espi et al.

Summary: Patients on maintenance hemodialysis (MHD) show weakened immune responses after receiving two doses of mRNA vaccine, but those with a history of COVID-19 may benefit from a third vaccine injection based on their stronger response to the vaccine.

KIDNEY INTERNATIONAL (2021)

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Article Biochemistry & Molecular Biology

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

David S. Khoury et al.

Summary: The level of neutralizing antibodies is closely related to immune protection against COVID-19, playing a crucial role in protecting against detected infection and severe infection. Studies have shown that neutralizing titers will decline over time after vaccination, leading to decreased protection against SARS-CoV-2 infection.

NATURE MEDICINE (2021)

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Letter Surgery

Strong antibody response after a first dose of a SARS-CoV-2 mRNA-based vaccine in kidney transplant recipients with a previous history of COVID-19

Ilies Benotmane et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2021)

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Letter Urology & Nephrology

Occurrence of severe COVID-19 in vaccinated transplant patients

Sophie Caillard et al.

KIDNEY INTERNATIONAL (2021)

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Article Multidisciplinary Sciences

BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

Ugur Sahin et al.

Summary: The BNT162b2 vaccine shows 95% efficacy in preventing COVID-19 by boosting neutralizing antibody titres and activating specific T cell responses. The vaccine-induced immune response is broad and stable, lasting for a prolonged period, providing good coverage against various SARS-CoV-2 variants.

NATURE (2021)

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Article Urology & Nephrology

An initial report from the French SOT COVID Registry suggests high mortality due to COVID-19 in recipients of kidney transplants

Sophie Caillard et al.

KIDNEY INTERNATIONAL (2020)

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Review Biotechnology & Applied Microbiology

mRNA vaccines - a new era in vaccinology

Norbert Pardi et al.

NATURE REVIEWS DRUG DISCOVERY (2018)

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COVID-19 vaccination in kidney transplant recipients

相关参考文献

The ROMANOV study found impaired humoral and cellular immune responses to SARS-CoV-2 mRNA vaccine in virus-unexposed patients receiving maintenance hemodialysis

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

Strong antibody response after a first dose of a SARS-CoV-2 mRNA-based vaccine in kidney transplant recipients with a previous history of COVID-19

Occurrence of severe COVID-19 in vaccinated transplant patients

BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

An initial report from the French SOT COVID Registry suggests high mortality due to COVID-19 in recipients of kidney transplants

mRNA vaccines - a new era in vaccinology

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