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A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16ecto directed chimeric antigen receptors for recurrent ovarian cancer
Mythili Koneru et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Risk of solid cancer in patients exposed to anti-tumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis
Louise K. Mercer et al.
ANNALS OF THE RHEUMATIC DISEASES (2015)
Carlumab, an anti-C-C chemokine ligand 2 monoclonal antibody, in combination with four chemotherapy regimens for the treatment of patients with solid tumors: an open-label, multicenter phase 1b study
Irene Brana et al.
TARGETED ONCOLOGY (2015)
Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy
Carola H. Ries et al.
CANCER CELL (2014)
Interleukin 12: still a promising candidate for tumor immunotherapy?
Witold Lasek et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2014)
A Phase I Trial of LY2510924, a CXCR4 Peptide Antagonist, in Patients with Advanced Cancer
Matthew D. Galsky et al.
CLINICAL CANCER RESEARCH (2014)
PF-03446962, a fully-human monoclonal antibody against transforming growth-factor β (TGFβ) receptor ALK1, in pre-treated patients with urothelial cancer: an open label, single-group, phase 2 trial
A. Necchi et al.
INVESTIGATIONAL NEW DRUGS (2014)
Cancer-related inflammation and treatment effectiveness
Connie I. Diakos et al.
LANCET ONCOLOGY (2014)
Siltuximab for multicentric Castleman's disease: a randomised, double-blind, placebo-controlled trial
Frits van Rhee et al.
LANCET ONCOLOGY (2014)
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
Shannon L. Maude et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Phase I Study of GC1008 (Fresolimumab): A Human Anti-Transforming Growth Factor-Beta (TGFβ) Monoclonal Antibody in Patients with Advanced Malignant Melanoma or Renal Cell Carcinoma
John C. Morris et al.
PLOS ONE (2014)
IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
Koji Taniguchi et al.
SEMINARS IN IMMUNOLOGY (2014)
The immunocytokine NHS-IL12 as a potential cancer therapeutic
Jonathan Fallon et al.
ONCOTARGET (2014)
High dose interleukin-2 (Aldesleukin) - expert consensus on best management practices-2014
Janice P. Dutcher et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2014)
Durable responses and reversible toxicity of high-dose interleukin-2 treatment of melanoma and renal cancer in a Community Hospital Biotherapy Program
Roxanne Payne et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2014)
A review on CXCR4/CXCL12 axis in oncology: No place to hide
Urszula M. Domanska et al.
EUROPEAN JOURNAL OF CANCER (2013)
Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy
Wei Liao et al.
IMMUNITY (2013)
Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer
Kenneth J. Pienta et al.
INVESTIGATIONAL NEW DRUGS (2013)
Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey
Bharat B. Aggarwal et al.
BLOOD (2012)
IL-10 Directly Activates and Expands Tumor-Resident CD8+ T Cells without De Novo Infiltration from Secondary Lymphoid Organs
Jan Emmerich et al.
CANCER RESEARCH (2012)
Safety and Efficacy of Combination Immunotherapy With Interferon Alfa-2b and Tremelimumab in Patients With Stage IV Melanoma
Ahmad A. Tarhini et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Paraneoplastic Thrombocytosis in Ovarian Cancer
Rebecca L. Stone et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
A Pilot Study of IL-2Rα Blockade during Lymphopenia Depletes Regulatory T-cells and Correlates with Enhanced Immunity in Patients with Glioblastoma
John H. Sampson et al.
PLOS ONE (2012)
Cancer-related inflammation: Common themes and therapeutic opportunities
Frances R. Balkwill et al.
SEMINARS IN CANCER BIOLOGY (2012)
The role of interleukin-2 during homeostasis and activation of the immune system
Onur Boyman et al.
NATURE REVIEWS IMMUNOLOGY (2012)
IL-10 Elicits IFNγ-Dependent Tumor Immune Surveillance
John B. Mumm et al.
CANCER CELL (2011)
Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer
Jermaine Coward et al.
CLINICAL CANCER RESEARCH (2011)
Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: A Phase I/II Study in Metastatic Melanoma Patients
Joannes F. M. Jacobs et al.
CLINICAL CANCER RESEARCH (2010)
Clinical Use of Anti-CD25 Antibody Daclizumab to Enhance Immune Responses to Tumor Antigen Vaccination by Targeting Regulatory T cells
Andrew J. Rech et al.
CANCER VACCINES (2009)
Role of cytokine therapy for Renal Cell Carcinoma in the era of targeted agents
Sebastien J. Hotte et al.
Current Oncology (2009)
The role of differential expression of human interferon-A genes in antiviral immunity
Pierre Genin et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2009)
New insights into the regulation of T cells by γc family cytokines
Yrina Rochman et al.
NATURE REVIEWS IMMUNOLOGY (2009)
A clinical study assessing the tolerability and biological effects of infliximab, a TNF-α inhibitor, in patients with advanced cancer
E. R. Brown et al.
ANNALS OF ONCOLOGY (2008)
Randomized phase 3 trial of interferon gamma-1b plus standard carboplatin/paclitaxel versus carboplatin/paclitaxel alone for first-line treatment of advanced ovarian and primary peritoneal carcinomas: Results from a prospectively designed analysis of progression-free survival
David S. Alberts et al.
GYNECOLOGIC ONCOLOGY (2008)
Interferons at age 50: past, current and future impact on biomedicine
Ernest C. Borden et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Tumor necrosis factor α as a new target for renal cell carcinoma:: Two sequential phase II trials of infliximab at standard and high dose
Michelle L. Harrison et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Interleukin-12: Biological properties and clinical application
Michele Del Vecchio et al.
CLINICAL CANCER RESEARCH (2007)
A phase II open-label study of recombinant human interleukin-12 in patients with stage IA, IB, or IIA mycosis fungoides
Madeleine Duvic et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2006)
Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma
Richard F. Little et al.
BLOOD (2006)
Side effects of interferon-α therapy
S Sleijfer et al.
PHARMACY WORLD & SCIENCE (2005)
Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease
N Nishimoto et al.
BLOOD (2005)
Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene
MG Borrello et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma
DF McDermott et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Phase II clinical trial of interleukin-12 in patients with relapsed and refractory non-Hodgkin's lymphoma and Hodgkin's disease
A Younes et al.
CLINICAL CANCER RESEARCH (2004)
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
FR Greten et al.
CELL (2004)
The significance of cancer cell expression of the chemokine receptor CXCR4
F Balkwill
SEMINARS IN CANCER BIOLOGY (2004)
Interferon alfa therapy for malignant melanoma: A systematic review of randomized controlled trials
MB Lens et al.
JOURNAL OF CLINICAL ONCOLOGY (2002)