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Article
Urology & Nephrology
Benjamin Bowe et al.
Summary: This study aimed to describe rates and outcomes of AKI in a national cohort of US veterans hospitalized with COVID-19. The results showed that AKI was common in these patients and associated with higher risk of health care resource utilization and death, with nearly half of patients not recovering to baseline by discharge. Substantial geographic variation and temporal decline in rates and severity of AKI were observed.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Article
Medicine, General & Internal
Chaolin Huang et al.
Summary: This study aimed to investigate the long-term health consequences of discharged COVID-19 patients and associated risk factors, particularly disease severity. Patients with more severe illness during hospitalization showed more severe impaired pulmonary diffusion capacities and abnormal chest imaging manifestations, highlighting the need for targeted interventions for long-term recovery.
Article
Cardiac & Cardiovascular Systems
Alessandro Di Toro et al.
Summary: Long COVID, characterized by persistence of symptoms for at least 12 weeks after COVID-19 onset, presents a clinically heterogeneous condition with involvement of multiple organs/systems, including the cardiovascular system. Recurrent symptoms include fatigue, breathlessness, myalgia, headache, and impaired concentration, with potential cardiovascular manifestations such as palpitations and chest pain. Diagnostic criteria remain narrative-based with a need for shared diagnostic framework integrating biomarkers, imaging, and clinical monitoring for at-risk patients.
EUROPEAN HEART JOURNAL SUPPLEMENTS
(2021)
Article
Multidisciplinary Sciences
Yan Xie et al.
Summary: The study analyzed data from the US Department of Veterans Affairs healthcare databases to estimate the burden of Post-Acute Sequelae of SARS-CoV-2 infection (PASC), finding approximately 73.43 PASC cases per 1000 persons at 6 months. The burden of PASC varied by demographic groups and baseline health status, with more severe acute infection leading to higher burden. The study highlights the substantial burden of PASC and the importance of considering different population groups when planning healthcare strategies.
NATURE COMMUNICATIONS
(2021)
Review
Cardiac & Cardiovascular Systems
Mina K. Chung et al.
Summary: COVID-19, caused by SARS-CoV-2, has potential consequences on the cardiovascular health of millions of survivors worldwide. The virus can infect the heart, vascular tissues, and circulating cells through ACE2, leading to acute cardiac injury. This update reviews clinical manifestations, impact mechanisms, and management implications for patients after recovering from acute COVID-19 infection.
CIRCULATION RESEARCH
(2021)
Article
Multidisciplinary Sciences
Toni M. Delorey et al.
Summary: This study using single-cell and spatial atlases revealed the impact of COVID-19 infection on lung, kidney, liver, and heart tissues, showing structural remodeling and viral RNA enrichment. Differences in lung inflammatory responses and transcriptional alterations in heart tissue of COVID-19 patients were also identified, along with cell types and genes associated with disease severity.
Article
Multidisciplinary Sciences
Ziyad Al-Aly et al.
Summary: This study comprehensively describes the post-acute sequelae of COVID-19 using national healthcare databases, finding increased risk of death and use of health resources beyond the first 30 days of illness, as well as incident sequelae in various organ systems, increased use of therapeutic agents, and evidence of laboratory abnormalities. The findings show a risk gradient according to the severity of acute COVID-19 infection and highlight the burden of health loss experienced by patients who survive the acute phase.
Review
Biochemistry & Molecular Biology
Ani Nalbandian et al.
Summary: SARS-CoV-2 is responsible for the COVID-19 pandemic, causing global healthcare crises. Recovery from COVID-19 may lead to persistent symptoms and long-term complications, prompting the need for multidisciplinary care and follow-up for survivors.
Article
Multidisciplinary Sciences
Liguo Zhang et al.
Summary: Researchers have found that SARS-CoV-2 RNA may be reverse-transcribed and integrated into the DNA of human cells, leading to positive PCR results in patients even after infection and recovery. However, the integrated viral sequences mainly consist of subgenomic sequences, which cannot produce infectious virus.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Medicine, General & Internal
Daniel Ayoubkhani et al.
Summary: Patients discharged from the hospital after COVID-19 were found to have increased rates of multiorgan dysfunction, with higher risk not only limited to the elderly but also varying across ethnic groups.
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Article
Medicine, General & Internal
Sarah E. Daugherty et al.
Summary: The study evaluated the excess risk and relative hazards for developing incident clinical sequelae after the acute phase of SARS-CoV-2 infection in adults aged 18-65. The results show that individuals infected with SARS-CoV-2 may have a higher risk of developing new clinical sequelae after the acute phase compared to the control groups, with some sequelae more commonly seen in other viral illnesses.
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Article
Urology & Nephrology
Benjamin Bowe et al.
Summary: The study showed that survivors of COVID-19 had an increased risk of kidney outcomes in the post-acute phase of the disease, indicating the importance of paying attention to kidney disease in long-term COVID-19 care.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Article
Medicine, General & Internal
Ioannis Katsoularis et al.
Summary: This study in Sweden quantified the risk of acute myocardial infarction and ischaemic stroke associated with COVID-19, finding a significant correlation.
Editorial Material
Multidisciplinary Sciences
Andrew Briggs et al.
Editorial Material
Multidisciplinary Sciences
Nisreen A. Alwan
Article
Medicine, General & Internal
Miao Cai et al.
Summary: The study found that between March and September 2020, the 30-day mortality and hospitalisation rates of individuals infected with COVID-19 decreased significantly, primarily due to changes in the underlying characteristics of the affected population.
Review
Medicine, Research & Experimental
Farnaz Farshidfar et al.
Summary: The emergence of SARS-CoV-2 has led to a global pandemic with a high impact on public health. Apart from lung involvement, COVID-19 also affects the cardiovascular system, with preexisting cardiovascular disease increasing mortality in patients with the virus. Potential mechanisms for cardiovascular complications include direct viral infection and cytokine storm-induced myocarditis.
Article
Medicine, General & Internal
Hannah E. Davis et al.
Summary: Patients with Long COVID report prolonged, multisystem involvement and significant disability. By seven months, many patients have not yet recovered (mainly from systemic and neurological/cognitive symptoms), have not returned to previous levels of work, and continue to experience significant symptom burden.
Letter
Medicine, General & Internal
Zsuzsanna Varga et al.
Letter
Medicine, General & Internal
Angelo Carfi et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2020)
Review
Biochemistry & Molecular Biology
Aakriti Gupta et al.
Review
Cardiac & Cardiovascular Systems
Masataka Nishiga et al.
NATURE REVIEWS CARDIOLOGY
(2020)
Review
Public, Environmental & Occupational Health
Coady Wing et al.
ANNUAL REVIEW OF PUBLIC HEALTH, VOL 39
(2018)
Editorial Material
Medicine, General & Internal
Amy J. H. Kind et al.
NEW ENGLAND JOURNAL OF MEDICINE
(2018)
Editorial Material
Medicine, General & Internal
Justin B. Dimick et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2014)
Article
Public, Environmental & Occupational Health
Michele Jonsson Funk et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2011)
Article
Mathematics, Interdisciplinary Applications
Peter C. Austin
MULTIVARIATE BEHAVIORAL RESEARCH
(2011)
Article
Public, Environmental & Occupational Health
Marc Lipsitch et al.
Article
Public, Environmental & Occupational Health
Sebastian Schneeweiss et al.
