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mTORC2 forms iron-clad defense to guard memory

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NATURE IMMUNOLOGY
卷 23, 期 2, 页码 155-156

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NATURE PORTFOLIO
DOI: 10.1038/s41590-021-01100-2

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This study reveals that mTORC2 plays a crucial role in supporting the long-term survival of memory CD4(+) T cells by protecting them from a specific form of regulated cell death known as ferroptosis.
Long-term persistence of memory CD4(+) T cells is supported by mTORC2-dependent protection from a distinctive form of regulated cell death known as ferroptosis.

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