相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis
Jeffrey M. Granja et al.
NATURE GENETICS (2021)
Simplified Epigenome Profiling Using Antibody-tethered Tagmentation
Steven Henikoff et al.
BIO-PROTOCOL (2021)
KMT2A rearranged acute lymphoblastic leukaemia: Unravelling the genomic complexity and heterogeneity of this high-risk disease
Michelle O. Forgione et al.
CANCER LETTERS (2020)
The MLL/SET family and haematopoiesis
Eric T. B. Antunes et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2020)
Novel inhibitors of the histone methyltransferase DOT1L show potent antileukemic activity in patient-derived xenografts
Florian Perner et al.
BLOOD (2020)
An atlas of dynamic chromatin landscapes in mouse fetal development
David U. Gorkin et al.
NATURE (2020)
Efficient low-cost chromatin profiling with CUT&Tag
Hatice S. Kaya-Okur et al.
NATURE PROTOCOLS (2020)
Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation
Steven Henikoff et al.
ELIFE (2020)
The cis-Regulatory Atlas of the Mouse Immune System
Hideyuki Yoshida et al.
CELL (2019)
Peak calling by Sparse Enrichment Analysis for CUT&RUN chromatin profiling
Michael P. Meers et al.
EPIGENETICS & CHROMATIN (2019)
Rewiring the Epigenetic Networks in MLL-Rearranged Leukemias: Epigenetic Dysregulation and Pharmacological Interventions
Anthony K. N. Chan et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia
Andrei V. Krivtsov et al.
CANCER CELL (2019)
Critical role of Jumonji domain of JMJD1C in MLL-rearranged leukemia
Jesus Izaguirre-Carbonell et al.
BLOOD ADVANCES (2019)
The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
Hamid Bolouri et al.
NATURE MEDICINE (2018)
Recovering Gene Interactions from Single-Cell Data Using Data Diffusion
David van Dijk et al.
CELL (2018)
The genetic basis and cell of origin of mixed phenotype acute leukaemia
Thomas B. Alexander et al.
NATURE (2018)
Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs
Derek H. Janssens et al.
EPIGENETICS & CHROMATIN (2018)
Transcription control by the ENL YEATS domain in acute leukaemia
Michael A. Erb et al.
NATURE (2017)
MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia
K. H. M. Prange et al.
ONCOGENE (2017)
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia
Jon Kerry et al.
CELL REPORTS (2017)
MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches
Amanda C. Winters et al.
FRONTIERS IN PEDIATRICS (2017)
Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapy
Rebecca Gardner et al.
BLOOD (2016)
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
Daniel A. Arber et al.
BLOOD (2016)
Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia
Shan Lin et al.
CANCER CELL (2016)
Epigenetics of hematopoiesis and hematological malignancies
Deqing Hu et al.
GENES & DEVELOPMENT (2016)
deepTools2: a next generation web server for deep-sequencing data analysis
Fidel Ramirez et al.
NUCLEIC ACIDS RESEARCH (2016)
The molecular mechanics of mixed lineage leukemia
R. K. Slany
ONCOGENE (2016)
Lineage Switch in MLL-Rearranged Infant Leukemia Following CD19-Directed Therapy
Ahmad Rayes et al.
PEDIATRIC BLOOD & CANCER (2016)
The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias
Anna K. Andersson et al.
NATURE GENETICS (2015)
Myocyte enhancer factor 2C in hematopoiesis and leukemia
K. Cante-Barrett et al.
ONCOGENE (2014)
DOT1L Inhibitor EPZ-5676 Displays Synergistic Antiproliferative Activity in Combination with Standard of Care Drugs and Hypomethylating Agents in MLL-Rearranged Leukemia Cells
Christine R. Klaus et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2014)
Potent inhibition of DOT1L as treatment of MLL-fusion leukemia
Scott R. Daigle et al.
BLOOD (2013)
MLL-ENL Inhibits Polycomb Repressive Complex 1 to Achieve Efficient Transformation of Hematopoietic Cells
Emanuel Maethner et al.
CELL REPORTS (2013)
Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor
Scott R. Daigle et al.
CANCER CELL (2011)
MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L
Kathrin M. Bernt et al.
CANCER CELL (2011)
CBX8, a Polycomb Group Protein, Is Essential for MLL-AF9-Induced Leukemogenesis
Jiaying Tan et al.
CANCER CELL (2011)
MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia
Sara C. Monroe et al.
EXPERIMENTAL HEMATOLOGY (2011)
AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia
Chengqi Lin et al.
MOLECULAR CELL (2010)
Chromatin Signatures in Multipotent Human Hematopoietic Stem Cells Indicate the Fate of Bivalent Genes during Differentiation
Kairong Cui et al.
CELL STEM CELL (2009)
Histone modifications at human enhancers reflect global cell-type-specific gene expression
Nathaniel D. Heintzman et al.
NATURE (2009)
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia
Matthew G. Guenther et al.
GENES & DEVELOPMENT (2008)
Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential
Piu Wong et al.
GENES & DEVELOPMENT (2007)
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
BE Bernstein et al.
CELL (2006)
The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin
DT Zeisig et al.
ONCOGENE (2005)
Physical association and coordinate function of the H3K4 methyltransferase MLL1 and the H4K16 acetyltransferase MOF
YL Dou et al.
CELL (2005)
hDOT1L links histone methylation to leukemogenesis
Y Okada et al.
CELL (2005)
Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization
BB Zeisig et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Taspase1:: A threonine aspartase required for cleavage of MLL and proper HOX gene expression
JJD Hsieh et al.
CELL (2003)
Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization
JJD Hsieh et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
MLL targets SET domain methyltransferase activity to Hox gene promoters
TA Milne et al.
MOLECULAR CELL (2002)
MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein
P Ernst et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
分享论文
