相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The clinical features of polymerase proof-reading associated polyposis (PPAP) and recommendations for patient management
Claire Palles et al.
FAMILIAL CANCER (2022)
Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing
Peter Ellis et al.
NATURE PROTOCOLS (2021)
Somatic mutation landscapes at single-molecule resolution
Federico Abascal et al.
NATURE (2021)
Mutational signature in colorectal cancer caused by genotoxic pks+E. coli
Cayetano Pleguezuelos-Manzano et al.
NATURE (2020)
Pan-cancer analysis of whole genomes
Peter J. Campbell et al.
NATURE (2020)
Tobacco smoking and somatic mutations in human bronchial epithelium
Kenichi Yoshida et al.
NATURE (2020)
The repertoire of mutational signatures in human cancer
Ludmil B. Alexandrov et al.
NATURE (2020)
Genomic footprints of activated telomere maintenance mechanisms in cancer
Lina Sieverling et al.
NATURE COMMUNICATIONS (2020)
The mutational landscape of normal human endometrial epithelium
Luiza Moore et al.
NATURE (2020)
Pathogenic Mechanisms of Somatic Mutation and Genome Mosaicism in Aging
Jan Vijg et al.
CELL (2020)
Somatic Evolution in Non-neoplastic IBD-Affected Colon
Sigurgeir Olafsson et al.
CELL (2020)
Extensive heterogeneity in somatic mutation and selection in the human bladder
Andrew R. J. Lawson et al.
SCIENCE (2020)
TelomereHunter - in silico estimation of telomere content and composition from cancer genomes
Lars Feuerbach et al.
BMC BIOINFORMATICS (2019)
Oncogenic mutations in histologically normal endometrium: the new normal?
Vivian Lac et al.
JOURNAL OF PATHOLOGY (2019)
Somatic mutations and clonal dynamics in healthy and cirrhotic human liver
Simon F. Brunner et al.
NATURE (2019)
The landscape of somatic mutation in normal colorectal epithelial cells
Henry Lee-Six et al.
NATURE (2019)
The mutational footprints of cancer therapies
Oriol Pich et al.
NATURE GENETICS (2019)
5-Fluorouracil treatment induces characteristic T>G mutations in human cancer
Sharon Christenser et al.
NATURE COMMUNICATIONS (2019)
Mechanisms regulating zygotic genome activation
Katharine N. Schulz et al.
NATURE REVIEWS GENETICS (2019)
Embryonal precursors of Wilms tumor
Tim H. H. Coorens et al.
SCIENCE (2019)
The somatic mutation landscape of premalignant colorectal adenoma
Shu-Hong Lin et al.
GUT (2018)
Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response
Daniel Temko et al.
JOURNAL OF PATHOLOGY (2018)
Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data
James H. R. Farmery et al.
SCIENTIFIC REPORTS (2018)
Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae
Stephanie R. Barbari et al.
G3-GENES GENOMES GENETICS (2018)
Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load
Hao-Dong Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Prediction of acute myeloid leukaemia risk in healthy individuals
Sagi Abelson et al.
NATURE (2018)
Intra-tumour diversification in colorectal cancer at the single-cell level
Sophie F. Roerink et al.
NATURE (2018)
Population dynamics of normal human blood inferred from somatic mutations
Henry Lee-Six et al.
NATURE (2018)
Clonal Expansion and Diversification of Cancer-Associated Mutations in Endometriosis and Normal Endometrium
Kazuaki Suda et al.
CELL REPORTS (2018)
Somatic mutant clones colonize the human esophagus with age
Inigo Martincorena et al.
SCIENCE (2018)
Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis
Fernando G. Osorio et al.
CELL REPORTS (2018)
The COSMIC Cancer Gene Census: describing genetic dysfunction across all human cancers
Zbyslaw Sondka et al.
NATURE REVIEWS CANCER (2018)
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo
Young Seok Ju et al.
NATURE (2017)
Reduced mutation rate in exons due to differential mismatch repair
Joan Frigola et al.
NATURE GENETICS (2017)
Universal Patterns of Selection in Cancer and Somatic Tissues
Inigo Martincorena et al.
CELL (2017)
POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance
Fernando Bellido et al.
GENETICS IN MEDICINE (2016)
Timing, rates and spectra of human germline mutation
Raheleh Rahbari et al.
NATURE GENETICS (2016)
Tissue-specific mutation accumulation in human adult stem cells during life
Francis Blokzijl et al.
NATURE (2016)
JBrowse: a dynamic web platform for genome visualization and analysis
Robert Buels et al.
GENOME BIOLOGY (2016)
Clock-like mutational processes in human somatic cells
Ludmil B. Alexandrov et al.
NATURE GENETICS (2015)
High burden and pervasive positive selection of somatic mutations in normal human skin
Inigo Martincorena et al.
SCIENCE (2015)
Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication
Eve Shinbrot et al.
GENOME RESEARCH (2014)
Genome sequencing of normal cells reveals developmental lineages and mutational processes
Sam Behjati et al.
NATURE (2014)
Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging
Laila Ritsma et al.
NATURE (2014)
Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
Giulio Genovese et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
Siddhartha Jaiswal et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Integrated genomic characterization of endometrial carcinoma
Gad Getz et al.
NATURE (2013)
Signatures of mutational processes in human cancer
Ludmil B. Alexandrov et al.
NATURE (2013)
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas
Claire Palles et al.
NATURE GENETICS (2013)
Mutational Processes Molding the Genomes of 21 Breast Cancers
Serena Nik-Zainal et al.
CELL (2012)
Comprehensive molecular characterization of human colon and rectal cancer
Donna M. Muzny et al.
NATURE (2012)
The high fidelity and unique error signature of human DNA polymerase ε
Dagmara A. Korona et al.
NUCLEIC ACIDS RESEARCH (2011)
Integrative DNA Methylation and Gene Expression Analyses Identify DNA Packaging and Epigenetic Regulatory Genes Associated with Low Motility Sperm
Sara E. Pacheco et al.
PLOS ONE (2011)
Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells
Hugo J. Snippert et al.
CELL (2010)
Allele-specific copy number analysis of tumors
Peter Van Loo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift
Carlos Lopez-Garcia et al.
SCIENCE (2010)
High fidelity and lesion bypass capability of human DNA polymerase delta
Michael W. Schmitt et al.
BIOCHIMIE (2009)
DNA polymerase ε and δ proofreading suppress discrete mutator and cancer phenotypes in mice
Tina M. Albertson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
Peter J. Campbell et al.
NATURE GENETICS (2008)
Mutation at the polymerase active site of mouse DNA polymerase δ increases genomic instability and accelerates tumorigenesis
Ranga N. Venkatesan et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Identification of stem cells in small intestine and colon by marker gene Lgr5
Nick Barker et al.
NATURE (2007)
Yeast DNA polymerase ε participates in leading-strand DNA replication
Zachary F. Pursell et al.
SCIENCE (2007)
Hierarchical Dirichlet processes
Yee Whye Teh et al.
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION (2006)
Saccharomyces cerevisiae DNA polymerase δ -: High fidelity for base substitutions but lower fidelity for single- and multi-base deletions
JM Fortune et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Evidence of the monoclonal composition of human endometrial epithelial glands and mosaic pattern of clonal distribution in luminal epithelium
M Tanaka et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
High incidence of epithelial cancers in mice deficient for DNA polymerase δ proofreading
RE Goldsby et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Defective DNA polymerase-δ proofreading causes cancer susceptibility in mice
RE Goldsby et al.
NATURE MEDICINE (2001)
分享论文
