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Olga M. Mazina et al.
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Pedro A. Mateos-Gomez et al.
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Jinhua Han et al.
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Pedro A. Mateos-Gomez et al.
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David W. Wyatt et al.
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Rahul Bhowmick et al.
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Sotirios K. Sotiriou et al.
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Roles of eukaryotic topoisomerases in transcription, replication and genomic stability
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Raphael Ceccaldi et al.
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Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination
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RPA antagonizes microhomology-mediated repair of DNA double-strand breaks
Sarah K. Deng et al.
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Reconstitution of recombination-associated DNA synthesis with human proteins
Jessica L. Sneeden et al.
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BRCA1 and BRCA2: different roles in a common pathway of genome protection
Rohini Roy et al.
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Rad52 inactivation is synthetically lethal with BRCA2 deficiency
Zhihui Feng et al.
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Aura Carreira et al.
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X-irradiation of cells on glass slides has a dose doubling impact
Peter Kegel et al.
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XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
P Ahnesorg et al.
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M Seki et al.
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BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
HJ Yang et al.
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Biallelic inactivation of BRCA2 in Fanconi anemia
NG Howlett et al.
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AZ Stasiak et al.
CURRENT BIOLOGY (2000)
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