期刊
NATURAL PRODUCT RESEARCH
卷 37, 期 7, 页码 1212-1216出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2021.1986496
关键词
Streptomyces avermitilis AVE-H39; NTG-induced mutation; beta-class milbemycin; nematocidal activity
A new beta-class milbemycin, 13 alpha-hydroxy milbemycin beta(6) (1), was isolated from the fermentation broth of a mutant of genetically engineered strain Streptomyces avermitilis AVE-H39. Its structure and absolute configuration were elucidated by extensive spectroscopic methods and confirmed by single crystal X-ray diffraction.
A new beta-class milbemycin, 13 alpha-hydroxy milbemycin beta(6) (1), was isolated from the fermentation broth of a mutant of genetically engineered strain Streptomyces avermitilis AVE-H39. Its structure and absolute configuration were elucidated by extensive spectroscopic methods and confirmed by single crystal X-ray diffraction. [GRAPHICS]
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