4.6 Article

Comparative study of the transcriptomes of Caco-2 cells cultured under dynamic vs. static conditions following exposure to titanium dioxide and zinc oxide nanomaterials

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Summary: Dynamic culture conditions in gut-on-chip devices can mimic the in vivo intestinal environment and impact the gene expression of Caco-2 cells. The study shows that under dynamic culture conditions, gene expression patterns similar to those of the intestines in vivo were observed.

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