A novel phage display based platform for exosome diversity characterization

We present an innovative approach allowing the identification, isolation, and molecular characterization of disease-related exosomes based on their different antigenic reactivities. The designed strategy could be immediately translated into any disease in which exosomes are involved. The identification of specific markers and their subsequent association with exosome subtypes, together with the possibility to engineer target-guided exosome-like particles, could represent the key for the effective adoption of exosomes in clinical practice.

Automated summary

This study presents an innovative approach to identify, isolate, and characterize disease-related exosomes based on their antigenic reactivities. The strategy can be immediately applied to any disease involving exosomes. The identification of specific markers and their association with exosome subtypes, along with the engineering of target-guided exosome-like particles, could be crucial for the effective clinical adoption of exosomes.