4.6 Review

Abietane Diterpenes of the Genus Plectranthus sensu lato

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Article Chemistry, Applied

Anti-MRSA activity of abietane diterpenes from Coleus blumei Benth.

Sabina Jurkaninova et al.

Summary: Two previously unknown abietane diterpenes were isolated from Coleus blumei Benth., showing good antibacterial activity against methicillin-resistant Staphylococcus aureus subsp. aureus CCM 4750 (MRSA). Sincoetsin C was found to be the most active compound against MRSA 4750.

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Diterpenoids from Leaves of Cultivated Plectranthus ornatus

Lidivania Silva Freitas Mesquita et al.

Summary: Two new diterpenoid derivatives were isolated from the leaves of Plectranthus ornatus Codd, and their structures and biological activities were investigated. The compounds showed moderate cytotoxicity against human cancer cell lines.

PLANTA MEDICA (2021)

Article Plant Sciences

Antimycobacterial, Cytotoxic, and Antioxidant Activities of Abietane Diterpenoids Isolated from Plectranthus madagascariensis

Kadidiatou O. Ndjoubi et al.

Summary: Plectranthus madagascariensis, a medicinal plant native to South Africa, has shown potential in the treatment of tuberculosis and psoriasis due to its bioactive compounds with antimicrobial and antioxidant properties. The phytochemical studies of this plant led to the isolation of five known royleanone abietanes, which showed promising results in inhibiting Mycobacterium tuberculosis and demonstrating comparable toxicity to tamoxifen against HaCaT cells. The plant is considered an important ethnomedicinal plant and a promising source of diterpenoids for potential therapeutic applications.

PLANTS-BASEL (2021)

Review Biochemistry & Molecular Biology

Differences in diterpenoid diversity reveal new evidence for separating the genus Coleus from Plectranthus

Renee J. Grayer et al.

Summary: The research found significant differences in diterpenoids between the genera Coleus, Plectranthus, and Equilabium, providing strong support for their taxonomic classification. Coleus is characterized by abietanes oxygenated at C-14, while Plectranthus sensu stricto lacks C-14 oxygenation in abietanes.

NATURAL PRODUCT REPORTS (2021)

Article Biochemistry & Molecular Biology

Insight the Biological Activities of Selected Abietane Diterpenes Isolated from Plectranthus spp.

Przemyslaw Sitarek et al.

BIOMOLECULES (2020)

Article Pharmacology & Pharmacy

Antiprotozoal activity of diterpenoids isolated from Zhumeria majdae- absolute configuration by circular dichroism

Reza Zadali et al.

DARU-JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

Article Biochemistry & Molecular Biology

Plectrabarbene, a New Abietane Diterpene from Plectranthus barbatus Aerial Parts

Nawal M. Al Musayeib et al.

MOLECULES (2020)

Article Chemistry, Medicinal

Diterpenoids from Plectranthus spp. as Potential Chemotherapeutic Agents via Apoptosis

Tomasz Sliwinski et al.

PHARMACEUTICALS (2020)

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New diterpenoid glucoside and flavonoids from Plectranthus scutellarioides (L.) R. Br.

R. Kubinova et al.

SOUTH AFRICAN JOURNAL OF BOTANY (2019)

Article Chemistry, Multidisciplinary

Cytotoxic Activity of Royleanone Diterpenes from Plectranthus madagascariensis Benth

Diogo Matias et al.

ACS OMEGA (2019)

Article Chemistry, Medicinal

Anticancer properties of the abietane diterpene 6,7-dehydroroyleanone obtained by optimized extraction

Catarina Garcia et al.

FUTURE MEDICINAL CHEMISTRY (2018)

Article Biochemistry & Molecular Biology

Anti-inflammatory and antiproliferative diterpenoids from Plectranthus scutellarioides

Sylvian Cretton et al.

PHYTOCHEMISTRY (2018)

Article Plant Sciences

Phylogenetic study of Plectranthus, Coleus and allies (Lamiaceae): taxonomy, distribution and medicinal use

Alan Paton et al.

BOTANICAL JOURNAL OF THE LINNEAN SOCIETY (2018)

Review Pharmacology & Pharmacy

Naturally Occurring Plectranthus-derived Diterpenes with Antitumoral Activities

Catarina Garcia et al.

CURRENT PHARMACEUTICAL DESIGN (2018)

Article Chemistry, Multidisciplinary

Miscellaneous Diterpenes from the Aerial Parts of Plectranthus ornatus Codd

Fabio N. Avila et al.

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY (2017)

Article Plant Sciences

Antiparasitic Activity of Diterpenoids Against Trypanosoma cruzi

Sergio Alegre-Gomez et al.

PLANTA MEDICA (2017)

Article Biochemistry & Molecular Biology

Antimicrobial Abietane-Type Diterpenoids from Plectranthus punctatus

Negera Abdissa et al.

MOLECULES (2017)

Article Pharmacology & Pharmacy

Reactivity of Diterpenoid Quinones: Royleanones

Diogo Ladeiras et al.

CURRENT PHARMACEUTICAL DESIGN (2016)

Review Biochemistry & Molecular Biology

Aromatic abietane diterpenoids: their biological activity and synthesis

Miguel A. Gonzalez

NATURAL PRODUCT REPORTS (2015)

Article Biochemistry & Molecular Biology

In Vitro Antiprotozoal Activity of Abietane Diterpenoids Isolated from Plectranthus barbatus Andr.

Ramzi A. Mothana et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Article Biochemistry & Molecular Biology

Antimicrobial and enzyme inhibitory activities of the constituents of Plectranthus madagascariensis (Pers.) Benth

Renata Kubinova et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Polyphenols and diterpenoids from Plectranthus forsteri 'Marginatus'

R. Kubinova et al.

BIOCHEMICAL SYSTEMATICS AND ECOLOGY (2013)

Article Chemistry, Multidisciplinary

A New Abietane Diterpenoid from Plectranthus bishopianus BENTH.

Kodakandla Venkata Syamasundar et al.

HELVETICA CHIMICA ACTA (2012)

Article Biochemistry & Molecular Biology

In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica

M. Fronza et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2011)

Review Biochemistry & Molecular Biology

The Genus Plectranthus in India and Its Chemistry

Shobha Waldia et al.

CHEMISTRY & BIODIVERSITY (2011)

Article Plant Sciences

Plectranthus: A plant for the future?

L. J. Rice et al.

SOUTH AFRICAN JOURNAL OF BOTANY (2011)

Article Biochemistry & Molecular Biology

Distribution of exudate flavonoids in the genus Plectranthus

Renee J. Grayer et al.

BIOCHEMICAL SYSTEMATICS AND ECOLOGY (2010)

Article Plant Sciences

Two new diterpenoids from Plectranthus species

Maria Fatima Simoes et al.

PHYTOCHEMISTRY LETTERS (2010)

Article Plant Sciences

Bioactive Diterpenes from the Aerial Parts of Anisochilus harmandii

Ratsami Lekphrom et al.

PLANTA MEDICA (2010)

Article Oncology

Inhibition of tumor cell proliferation by coleon C

Xiu Xing et al.

JOURNAL OF CHEMOTHERAPY (2008)

Article Chemistry, Applied

Terpenoids and phenolics from Plectranthus strigosus, bioactivity screening

Cristina Gaspar-Marques et al.

NATURAL PRODUCT RESEARCH (2008)

Article Chemistry, Multidisciplinary

Abietane diterpenoids isolation from Plectranthus barbatus

Roberto L. de Albuquerque et al.

QUIMICA NOVA (2007)

Article Biochemistry & Molecular Biology

Further diterpenoids from Plectranthus ornatus and P-grandidentatus

Patricia Rijo et al.

BIOCHEMICAL SYSTEMATICS AND ECOLOGY (2007)

Review Biochemistry & Molecular Biology

Occurrence, biological activities and synthesis of kaurane diterpenes and their glycosides

Pablo Anselmo Garcia et al.

MOLECULES (2007)

Article Biochemistry & Molecular Biology

Insect-antifeedant and antibacterial activity of diterpenoids from species of Plectranthus

Julia Wellsow et al.

PHYTOCHEMISTRY (2006)

Review Plant Sciences

Plectranthus:: A review of ethnobotanical uses

CW Lukhoba et al.

JOURNAL OF ETHNOPHARMACOLOGY (2006)

Article Biochemistry & Molecular Biology

Effect of abietane diterpenes from Plectranthus grandidentatus on T- and B-lymphocyte proliferation

F Cerqueira et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2004)

Article Chemistry, Multidisciplinary

Abietanes and a novel 20-norabietanoid from Plectranthus cyaneus (Lamiaceae)

T Horvath et al.

HELVETICA CHIMICA ACTA (2004)

Article Plant Sciences

Abietane diterpenoids from Coleus xanthanthus

SX Mei et al.

JOURNAL OF NATURAL PRODUCTS (2002)

Review Biochemistry & Molecular Biology

Chemistry of the genus Plectranthus

M Abdel-Mogib et al.

MOLECULES (2002)

Article Chemistry, Medicinal

Two new diterpenoids from Plectranthus nummularius BRIQ.

Y Narukawa et al.

CHEMICAL & PHARMACEUTICAL BULLETIN (2001)

Article Chemistry, Medicinal

Diastereomeric diterpenes from Coleus blumei

CY Ragasa et al.

CHEMICAL & PHARMACEUTICAL BULLETIN (2001)