4.6 Review

Controlled Drug Delivery Systems: Current Status and Future Directions

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Neurosciences

Nanotechnology: Its Application in Treating Neurodegenerative Diseases

Falaq Naz et al.

Summary: Neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's disease have a significant impact on quality of life, but current treatment strategies often face limitations in crossing the Blood-Brain Barrier. Nanotechnology shows promise in addressing these challenges over the past 20 years.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2021)

Review Nanoscience & Nanotechnology

Carbon Nanotubes: Smart Drug/GeneDelivery Carriers

Hossein Zare et al.

Summary: Carbon nanotubes have unique properties that make them suitable for drug and gene delivery, as well as applications in cancer therapy, anti-inflammatory treatments, and phototherapy. However, concerns about nanotoxicity and environmental impact remain, despite decades of research and potential benefits.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Article Polymer Science

Degradable Redox-Responsive Polyolefins

Christina M. Geiselhart et al.

Summary: The synthesis of long-chain aliphatic metathesis polymers containing redox-responsive TMBQ units is introduced in this study. The on-demand degradation of the polymer into small molecules upon the addition of a reductant such as Na2S2O4 is demonstrated, with the cleaved TMBQ unit recovered with high purity for recyclable redox polymers. Additionally, redox polymers with tailored functional properties are obtained through postpolymerization modification of the olefinic backbone with bromine and pentafluorophenyl motifs, expanding the scope of possible applications.

MACROMOLECULES (2021)

Review Pharmacology & Pharmacy

Emerging Role of Hydrogels in Drug Delivery Systems, Tissue Engineering and Wound Management

Shery Jacob et al.

Summary: Hydrogels are popular biomaterials known for their tunable physical properties, encapsulation capabilities, water holding capacity, and degradability. This review extensively discusses functionalization strategies and applications, covering different cross-linking techniques, materials, advantages, and disadvantages of hydrogels in drug delivery systems and wound dressing materials. Their unique features make hydrogels promising in the fields of drug delivery systems and applied biomedicine.

PHARMACEUTICS (2021)

Review Pharmacology & Pharmacy

Nanocarriers for targeted drug delivery

Afzal Shah et al.

Summary: The application of nanotechnology in targeted drug delivery systems is attracting extensive attention for its potential to improve drug delivery efficiency and concentration. Nanocarriers can enhance the biological distribution of drugs and cross the blood brain barrier, making them effective tools for drug delivery.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

Review Biochemistry & Molecular Biology

Graphene Oxide-Based Stimuli-Responsive Platforms for Biomedical Applications

Tejal V. Patil et al.

Summary: Graphene, a two-dimensional sp(2) hybridized carbon material, has garnered significant attention for its excellent properties in stimuli-responsive applications. Stimuli-responsive materials in the biomedical field are of particular interest for their potential to change behavior under different conditions, with graphene-based materials showing superior biocompatibility and various applications.

MOLECULES (2021)

Article

Application of Quantum Dots in Drug Delivery

Subham Jain N. et al.

Nanoscience and Nanotechnology - Asia (2021)

Article Biochemistry & Molecular Biology

Heparin-Tagged PLA-PEG Copolymer-Encapsulated Biochanin A-Loaded (Mg/Al) LDH Nanoparticles Recommended for Non-Thrombogenic and Anti-Proliferative Stent Coating

Shivakalyani Adepu et al.

Summary: Drug-eluting stents are widely used to prevent neointimal hyperplasia, and new coatings using herbal anti-proliferative agents and heparin-tagged polymers offer non-thrombogenic properties, sustained drug release, and complete degradation within 14 weeks.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Pharmacology & Pharmacy

Narrow Therapeutic Index drugs: clinical pharmacology perspective

Sam Habet

Summary: This study discusses the identification of drugs with Narrow Therapeutic Index (NTI), pointing out that the current definitions are controversial, the lists are arbitrary, and variability may affect safety and efficacy. The objectives include facilitating consensus on NTI definition, identifying characteristics, and developing criteria for identification. The FDA should consider PK studies as well as comparative efficacy and safety studies for NTI drugs.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2021)

Review Chemistry, Multidisciplinary

Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes

Mina Zare et al.

Summary: Electrospinning is a cost-effective and powerful method for producing nanofibers using a polymer solution and strong electric field, with applications in diverse biological and medical fields. It is particularly promising for manufacturing drug delivery systems due to its large surface area, controllable properties, and high biocompatibility. Electrospinning can improve solubility, bioavailability, and drug targeting, and has also been successful in encapsulating nutraceuticals, such as probiotics.

NANOMATERIALS (2021)

Article Multidisciplinary Sciences

Drug release behaviour and mechanism from unmodified and in situ modified bacterial cellulose

Shivakalyani Adepu et al.

Summary: Bacterial cellulose modified in situ by adding PEG2000 affects the microstructure and drug release kinetics, increasing porosity and pore volume while decreasing specific surface area, without significant impact on crystallinity. The modification facilitates a burst release of drugs compared to pristine BC, highlighting possibilities for immediate and sustained drug release applications.

PROCEEDINGS OF THE INDIAN NATIONAL SCIENCE ACADEMY (2021)

Article Engineering, Biomedical

Smart biomaterials-A proposed definition and overview of the field

Shukufe Amukarimi et al.

Summary: The emergence of smart biomaterials with responsive characteristics has expanded the boundaries of modern medicine, enabling important applications in tissue engineering, drug delivery systems, etc. They can guide stem cells for tissue regeneration, possess functions like smart drug delivery and self-folding release, and can form intelligent constructs resembling natural tissues.

CURRENT OPINION IN BIOMEDICAL ENGINEERING (2021)

Review Medicine, Research & Experimental

Engineering exosomes for targeted drug delivery

Yujie Liang et al.

Summary: Exosomes can be engineered through genetic and chemical methods for targeted drug delivery, increasing the local concentration of therapeutics and minimizing side effects.

THERANOSTICS (2021)

Review Nanoscience & Nanotechnology

Reduction-responsive polymers for drug delivery in cancer therapy-Is there anything new to discover?

Patricia F. Monteiro et al.

Summary: This article discusses the importance of reduction-responsive polymers as drug delivery systems and their potential applications in disease treatment. The authors emphasize the significance of these systems for targeting diseases with hypoxic regions, and highlight the challenges that may be encountered in the clinical translation of nanocarriers.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2021)

Article Materials Science, Biomaterials

Recent pros and cons of nanomaterials in drug delivery systems

Ulku Anik et al.

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS (2020)

Review Biotechnology & Applied Microbiology

Application of the Nano-Drug Delivery System in Treatment of Cardiovascular Diseases

Yudi Deng et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Review Pharmacology & Pharmacy

Ultrasound-Responsive Materials for Drug/Gene Delivery

Xiaowen Cai et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Chemistry, Multidisciplinary

Functionalized silk fibroin nanofibers as drug carriers: Advantages and challenges

Mehdi Farokhi et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Genetics & Heredity

Exosomes: Structure, Biogenesis, Types and Application in Diagnosis and Gene and Drug Delivery

Shriya Agarwal et al.

CURRENT GENE THERAPY (2020)

Review Pharmacology & Pharmacy

3D printing for drug delivery and biomedical applications

Sarwar Beg et al.

DRUG DISCOVERY TODAY (2020)

Review Pharmacology & Pharmacy

Application of mesoporous silica nanoparticles as drug delivery carriers for chemotherapeutic agents

Yasmine Alyassin et al.

DRUG DISCOVERY TODAY (2020)

Article Nanoscience & Nanotechnology

Comparative study of nanoparticle uptake and impact in murine lung, liver and kidney tissue slices

Roberta Bartucci et al.

NANOTOXICOLOGY (2020)

Review Pharmacology & Pharmacy

An overview of recent development in therapeutic drug carrier system using carbon nanotubes

M. A. Saleemi et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

Review Biochemistry & Molecular Biology

Applications and Limitations of Dendrimers in Biomedicine

Adriana Aurelia Chis et al.

MOLECULES (2020)

Article Pharmacology & Pharmacy

Cathepsin B-Responsive Liposomes for Controlled Anticancer Drug Delivery in Hep G2 Cells

Seulgi Lee et al.

PHARMACEUTICS (2020)

Review Biochemistry & Molecular Biology

pH-Sensitive Biomaterials for Drug Delivery

Shijie Zhuo et al.

MOLECULES (2020)

Article Polymer Science

Supramolecular hydrogels: Mechanical strengthening with dynamics

Yujie Li et al.

POLYMER (2020)

Review Chemistry, Multidisciplinary

A sodium alginate-based sustained-release IPN hydrogel and its applications

Zuhao Zou et al.

RSC ADVANCES (2020)

Review Biochemistry & Molecular Biology

Solid Lipid Nanoparticles for Drug Delivery: Pharmacological and Biopharmaceutical Aspects

Sebastian Scioli Montoto et al.

FRONTIERS IN MOLECULAR BIOSCIENCES (2020)

Article Materials Science, Multidisciplinary

Bacterial cellulose with microencapsulated antifungal essential oils: A novel double barrier release system

Shivakalyani Adepu et al.

MATERIALIA (2020)

Review Materials Science, Biomaterials

Thermoresponsive polymers and their biomedical application in tissue engineering - a review

Falko Doberenz et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Review Pharmacology & Pharmacy

Electrospun nanofibers for customized drug-delivery systems

Sasa Kajdic et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2019)

Review Polymer Science

pH-Responsive Polymer Nanoparticles for Drug Delivery

Nayeleh Deirram et al.

MACROMOLECULAR RAPID COMMUNICATIONS (2019)

Review Chemistry, Analytical

Molecularly Imprinted Polymer Based Sensors for Medical Applications

Yeseren Saylan et al.

SENSORS (2019)

Article Pharmacology & Pharmacy

A Smart pH-Sensitive Delivery System for Enhanced Anticancer Efficacy via Paclitaxel Endosomal Escape

Yihua Yang et al.

FRONTIERS IN PHARMACOLOGY (2019)

Review Engineering, Biomedical

Advances in injectable self-healing biomedical hydrogels

Yujie Tu et al.

ACTA BIOMATERIALIA (2019)

Review Pharmacology & Pharmacy

An overview of active and passive targeting strategies to improve the nanocarriers efficiency to tumour sites

Mohamed F. Attia et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2019)

Article Biochemistry & Molecular Biology

Reversible Thermoresponsive Peptide-PNIPAM Hydrogels for Controlled Drug Delivery

Meiwen Cao et al.

BIOMACROMOLECULES (2019)

Review Pharmacology & Pharmacy

Shaping the future: recent advances of 3D printing in drug delivery and healthcare

Sarah J. Trenfield et al.

EXPERT OPINION ON DRUG DELIVERY (2019)

Review Chemistry, Multidisciplinary

Enzyme responsive drug delivery systems in cancer treatment

Mahsa Shahriari et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Review Pharmacology & Pharmacy

Electric field-responsive nanoparticles and electric fields: physical, chemical, biological mechanisms and therapeutic prospects

Jelena Kolosnjaj-Tabi et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Review Chemistry, Multidisciplinary

Nanocarriers for drug delivery applications

Munusamy Chamundeeswari et al.

ENVIRONMENTAL CHEMISTRY LETTERS (2019)

Review Biochemistry & Molecular Biology

Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

Akhand Pratap Singh et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2019)

Review Pharmacology & Pharmacy

Transdermal patches: Design and current approaches to painless drug delivery

Othman A. Al Hanbali et al.

ACTA PHARMACEUTICA (2019)

Article Materials Science, Multidisciplinary

Broad-spectrum antimicrobial activity of bacterial cellulose silver nanocomposites with sustained release

Shivakalyani Adepu et al.

JOURNAL OF MATERIALS SCIENCE (2018)

Review Biochemistry & Molecular Biology

Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights

Maria Vallet-Regi et al.

MOLECULES (2018)

Review Chemistry, Multidisciplinary

Advances in Biomaterials for Drug Delivery

Owen S. Fenton et al.

ADVANCED MATERIALS (2018)

Article Biochemistry & Molecular Biology

NIR triggered liposome gold nanoparticles entrapping curcumin as in situ adjuvant for photothermal treatment of skin cancer

Surya Prakash Singh et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Biochemistry & Molecular Biology

Dendrimers for Drug Delivery

Abhay Singh Chauhan

MOLECULES (2018)

Review Biotechnology & Applied Microbiology

Nanoemulsions in drug delivery: formulation to medical application

Hossam H. Tayeb et al.

NANOMEDICINE (2018)

Review Pharmacology & Pharmacy

A Summary of Electrospun Nanofibers as Drug Delivery System: Drugs Loaded and Biopolymers Used as Matrices

Erick Jose Torres-Martinez et al.

CURRENT DRUG DELIVERY (2018)

Review Biotechnology & Applied Microbiology

Nano based drug delivery systems: recent developments and future prospects

Jayanta Kumar Patra et al.

JOURNAL OF NANOBIOTECHNOLOGY (2018)

Review Biotechnology & Applied Microbiology

Recent advancements in the use of exosomes as drug delivery systems

Edwin J. Bunggulawa et al.

JOURNAL OF NANOBIOTECHNOLOGY (2018)

Review Chemistry, Multidisciplinary

Magnetic Drug Delivery: Where the Field Is Going

Paige M. Price et al.

FRONTIERS IN CHEMISTRY (2018)

Review Pharmacology & Pharmacy

Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery

Sophia G. Antimisiaris et al.

PHARMACEUTICS (2018)

Review Physics, Fluids & Plasmas

Microbubble-Mediated Delivery for Cancer Therapy

Richard J. Browning et al.

FLUIDS (2018)

Review Nanoscience & Nanotechnology

Quantum dots in imaging, drug delivery and sensor applications

Cristian T. Matea et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

Review Pharmacology & Pharmacy

Functionalized single-walled carbon nanotubes: cellular uptake, biodistribution and applications in drug delivery

Zixian Li et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

Review Chemistry, Medicinal

Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy

Anish Babu et al.

MARINE DRUGS (2017)

Review Pharmacology & Pharmacy

Recent advances in light-responsive on-demand drug- delivery systems

Chase S. Linsley et al.

THERAPEUTIC DELIVERY (2017)

Review Materials Science, Biomaterials

Nano-engineered electro-responsive drug delivery systems

Yi Zhao et al.

JOURNAL OF MATERIALS CHEMISTRY B (2016)

Review Nanoscience & Nanotechnology

Designing hydrogels for controlled drug delivery

Jianyu Li et al.

NATURE REVIEWS MATERIALS (2016)

Article Chemistry, Multidisciplinary

Controlled Drug Delivery: Historical perspective for the next generation

Yeon Hee Yun et al.

JOURNAL OF CONTROLLED RELEASE (2015)

Article Polymer Science

Tunable LCST behavior of poly(N-isopropylacrylamide/ionic liquid) copolymers

Kamiya Jain et al.

POLYMER CHEMISTRY (2015)

Review Pharmacology & Pharmacy

Advances and Challenges of Liposome Assisted Drug Delivery

Lisa Sercombe et al.

FRONTIERS IN PHARMACOLOGY (2015)

Review Pharmacology & Pharmacy

Mesoporous silica nanoparticles in target drug delivery system: A review

Charu Bharti et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION (2015)

Review Chemistry, Multidisciplinary

Controlled drug delivery systems: Past forward and future back

Kinam Park

JOURNAL OF CONTROLLED RELEASE (2014)

Review Chemistry, Multidisciplinary

Sustained-release from nanocarriers: a review

Jayaganesh V. Natarajan et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Review Biotechnology & Applied Microbiology

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

Samir Mitragotri et al.

NATURE REVIEWS DRUG DISCOVERY (2014)

Article Materials Science, Biomaterials

Dendrimers for drug delivery

Anne-Marie Caminade et al.

JOURNAL OF MATERIALS CHEMISTRY B (2014)

Review Pharmacology & Pharmacy

Polymer-drug conjugates: Origins, progress to date and future directions

Jindrich Kopecek

ADVANCED DRUG DELIVERY REVIEWS (2013)

Review Pharmacology & Pharmacy

Liposomal drug delivery systems: From concept to clinical applications

Theresa M. Allen et al.

ADVANCED DRUG DELIVERY REVIEWS (2013)

Article Chemistry, Multidisciplinary

Drug Release from Electric-Field-Responsive Nanoparticles

Jun Ge et al.

ACS NANO (2012)

Review Chemistry, Multidisciplinary

Modeling of diffusion controlled drug delivery

Juergen Siepmann et al.

JOURNAL OF CONTROLLED RELEASE (2012)

Review Pharmacology & Pharmacy

Fluorescence nanoparticles quantum dots as drug delivery system and their toxicity: a review

Shirin Ghaderi et al.

JOURNAL OF DRUG TARGETING (2011)

Review Cell Biology

Quantum Dots in Cell Biology

Margarida M. Barroso

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2011)

Article Pharmacology & Pharmacy

Osmotically Controlled Drug Delivery System with Associated Drugs

Brahma P. Gupta et al.

JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES (2010)

Review Engineering, Biomedical

Stimuli-responsive polymers and their applications in drug delivery

Priya Bawa et al.

BIOMEDICAL MATERIALS (2009)

Article Pharmacology & Pharmacy

Use of the biopharmaceutical classification system in early drug development

M. Sherry Ku

AAPS JOURNAL (2008)

Review Biotechnology & Applied Microbiology

Transdermal drug delivery

Mark R. Prausnitz et al.

NATURE BIOTECHNOLOGY (2008)

Review Polymer Science

Hydrogels in drug delivery: Progress and challenges

Todd R. Hoare et al.

POLYMER (2008)

Article Biochemical Research Methods

Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers

Ina Hubatsch et al.

NATURE PROTOCOLS (2007)

Review Biochemistry & Molecular Biology

Drug Excipients

Huba Kalasz et al.

CURRENT MEDICINAL CHEMISTRY (2006)

Article Pharmacology & Pharmacy

Prediction of oral drug absorption in humans by theoretical passive absorption model

K Obata et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2005)

Review Biotechnology & Applied Microbiology

Current status and future potential of transdermal drug delivery

MR Prausnitz et al.

NATURE REVIEWS DRUG DISCOVERY (2004)

Review Chemistry, Physical

Liposome application: problems and prospects

Y Barenholz

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE (2001)