相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy
Meiou Dai et al.
NATURE COMMUNICATIONS (2021)
Modeling Breast Cancer Using CRISPR-Cas9-Mediated Engineering of Human Breast Organoids
Johanna F. Dekkers et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2020)
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
Richard Y. Ebright et al.
SCIENCE (2020)
Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors
Nevena B. Ognjenovic et al.
DEVELOPMENTAL CELL (2020)
Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging
Anne C. Rios et al.
CANCER CELL (2019)
The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads
Yang Liao et al.
NUCLEIC ACIDS RESEARCH (2019)
High-resolution 3D imaging of fixed and cleared organoids
Johanna F. Dekkers et al.
NATURE PROTOCOLS (2019)
AXIN deficiency in human and mouse hepatocytes induces hepatocellular carcinoma in the absence of beta-catenin activation
Shirley Abitbol et al.
JOURNAL OF HEPATOLOGY (2018)
Derivation of a robust mouse mammary organoid system for studying tissue dynamics
Paul R. Jamieson et al.
DEVELOPMENT (2017)
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
Robert T. Manguso et al.
NATURE (2017)
Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance
Richard Marcotte et al.
CELL (2016)
Proteogenomics connects somatic mutations to signalling in breast cancer
Philipp Mertins et al.
NATURE (2016)
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Serena Nik-Zainal et al.
NATURE (2016)
Mammary-Stem-Cell-Based Somatic Mouse Models Reveal Breast Cancer Drivers Causing Cell Fate Dysregulation
Zheng Zhang et al.
CELL REPORTS (2016)
A CRISPR/Cas9 Functional Screen Identifies Rare Tumor Suppressors
Alexandra Katigbak et al.
SCIENTIFIC REPORTS (2016)
A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1
Julie M. Sheridan et al.
BMC CANCER (2015)
Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
Sidi Chen et al.
CELL (2015)
Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer
Giovanni Ciriello et al.
CELL (2015)
An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo
Brandon J. Aubrey et al.
CELL REPORTS (2015)
PKA signaling drives mammary tumorigenesis through Src
A. G. Beristain et al.
ONCOGENE (2015)
Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library
Hiroko Koike-Yusa et al.
NATURE BIOTECHNOLOGY (2014)
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
Ophir Shalem et al.
SCIENCE (2014)
Analysis of Tumor Heterogeneity and Cancer Gene Networks Using Deep Sequencing of MMTV-Induced Mouse Mammary Tumors
Christiaan Klijn et al.
PLOS ONE (2013)
Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex
Vivian S. W. Li et al.
CELL (2012)
Conditional Disruption of Axin1 Leads to Development of Liver Tumors in Mice
Gui Jie Feng et al.
GASTROENTEROLOGY (2012)
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
Sohrab P. Shah et al.
NATURE (2012)
Comprehensive molecular portraits of human breast tumours
Daniel C. Koboldt et al.
NATURE (2012)
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
Christina Curtis et al.
NATURE (2012)
Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling
Madson Q. Almeida et al.
HUMAN MOLECULAR GENETICS (2010)
A scaling normalization method for differential expression analysis of RNA-seq data
Mark D. Robinson et al.
GENOME BIOLOGY (2010)
Axin determines cell fate by controlling the p53 activation threshold after DNA damage
Qinxi Li et al.
NATURE CELL BIOLOGY (2009)
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
Elgene Lim et al.
NATURE MEDICINE (2009)
An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ
Fariba Behbod et al.
BREAST CANCER RESEARCH (2009)
A β-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by Aida
Yanning Rui et al.
DEVELOPMENTAL CELL (2007)
MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer
Vassiliki Theodorou et al.
NATURE GENETICS (2007)
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
Ken Inoki et al.
CELL (2006)
Purification and unique properties of mammary epithelial stem cells
J Stingl et al.
NATURE (2006)
Generation of a functional mammary gland from a single stem cell
M Shackleton et al.
NATURE (2006)
Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice -: A model for Li-Fraumeni syndrome
C Kuperwasser et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development
DJ Jerry et al.
ONCOGENE (2000)
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
S Satoh et al.
NATURE GENETICS (2000)