4.6 Article

Neutrophil Extracellular Traps Exacerbate Ischemic Brain Damage

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Immunology

Filling the gaps on stroke research: Focus on inflammation and immunity

Damien Levard et al.

Summary: Over the past two decades, researchers have hoped for a new era in stroke treatment with a combination of reperfusion and neuroprotection, but despite positive results in preclinical stroke models, clinical trials have not shown efficacy. The existing preclinical data have depicted an incomplete picture of stroke pathophysiology, and there is a gap between clinical trials and preclinical results on stroke.

BRAIN BEHAVIOR AND IMMUNITY (2021)

Article Hematology

Neutrophil extracellular traps promote fibrous vascular occlusions in chronic thrombosis

Smriti Sharma et al.

Summary: The study reveals the significant role of neutrophil extracellular traps (NETs) in chronic thrombosis, with targeting these NETs potentially serving as a new therapeutic concept to treat thrombosis and prevent its sequelae.
Article Immunology

Elastase inhibitor agaphelin protects from acute ischemic stroke in mice by reducing thrombosis, blood ? brain barrier damage, and inflammation

Jonas Leinweber et al.

Summary: Recent research has shown that agaphelin has multiple antithrombotic effects and is protective in ischemic stroke. This protection is characterized by smaller infarct volume, reduced neurological deficits, and decreased animal mortality. Importantly, the protective effect of agaphelin does not increase the risk of intracerebral bleeding.

BRAIN BEHAVIOR AND IMMUNITY (2021)

Article Immunology

Therapeutic Targeting of Neutrophil Extracellular Traps Improves Primary and Secondary Intention Wound Healing in Mice

Annika Heuer et al.

Summary: The study found that targeting NETs through DNase1 treatment or genetic knockout can improve both primary and secondary intention wound healing, reduce healing time, and improve scar appearance. DNase1 treatment also decreases neutrophil activation and NETs formation.

FRONTIERS IN IMMUNOLOGY (2021)

Article Hematology

Neutrophil extracellular traps promote tPA-induced brain hemorrhage via cGAS in mice with stroke

Ranran Wang et al.

Summary: The infusion of tPA in acute ischemic stroke increases markers of NETs in the ischemic cortex and plasma, with upregulation of PAD4 enzyme. Disruption of NETs or inhibition of cGAS may reduce tPA-associated hemorrhage and BBB breakdown, suggesting potential therapeutic targets for thrombolytic therapy in ischemic stroke.
Article Clinical Neurology

Functional Dynamics of Neutrophils After Ischemic Stroke

Wei Cai et al.

TRANSLATIONAL STROKE RESEARCH (2020)

Article Multidisciplinary Sciences

NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture

Hawa Racine Thiam et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury

Kumar Vaibhav et al.

SCIENCE ADVANCES (2020)

Article Developmental Biology

Cellular Mechanisms of NETosis

Hawa Racine Thiam et al.

Annual Review of Cell and Developmental Biology (2020)

Article Multidisciplinary Sciences

DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25

Linbin Yang et al.

NATURE (2020)

Article Biochemistry & Molecular Biology

Adenosine Triphosphate Accumulated Following Cerebral Ischemia Induces Neutrophil Extracellular Trap Formation

Seung-Woo Kim et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Immunology

NETosis, complement, and coagulation: a triangular relationship

Cynthia M. de Bont et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2019)

Article Neurosciences

Neutrophil extracellular trap induced by HMGB1 exacerbates damages in the ischemic brain

Seung-Woo Kim et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)

Article Clinical Neurology

Microglial cell loss after ischemic stroke favors brain neutrophil accumulation

Amaia Otxoa-de-Amezaga et al.

ACTA NEUROPATHOLOGICA (2019)

Article Biochemistry & Molecular Biology

Citrullinated histone 3 causes endothelial barrier dysfunction

Jamie E. Meegan et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Review Biochemistry & Molecular Biology

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Lorenzo Galluzzi et al.

CELL DEATH AND DIFFERENTIATION (2018)

Review Immunology

Neutrophil Extracellular Traps in the Second Decade

Volker Brinkmann

JOURNAL OF INNATE IMMUNITY (2018)

Article Multidisciplinary Sciences

DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury

Shikai Wang et al.

SCIENTIFIC REPORTS (2018)

Article Multidisciplinary Sciences

Visualizing the function and fate of neutrophils in sterile injury and repair

Jing Wang et al.

SCIENCE (2017)

Article Multidisciplinary Sciences

Host DNases prevent vascular occlusion by neutrophil extracellular traps

Miguel Jimenez-Alcazar et al.

SCIENCE (2017)

Article Multidisciplinary Sciences

Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα

Yunmei Wang et al.

NATURE COMMUNICATIONS (2017)

Editorial Material Immunology

Neutrophil Extracellular Traps Open the Pandora's Box in Severe Malaria

Sebastian Boeltz et al.

FRONTIERS IN IMMUNOLOGY (2017)

Review Immunology

NETosis in Alzheimer's Disease

Enrica Caterina Pietronigro et al.

FRONTIERS IN IMMUNOLOGY (2017)

Article Clinical Neurology

Neutrophil Extracellular Traps in Ischemic Stroke Thrombi

Elodie Laridan et al.

ANNALS OF NEUROLOGY (2017)

Article Urology & Nephrology

Renoprotective Effects of DNAse-I Treatment in a Rat Model of Ischemia/Reperfusion-Induced Acute Kidney Injury

Victoria Peer et al.

AMERICAN JOURNAL OF NEPHROLOGY (2016)

Article Immunology

Formation of neutrophil extracellular traps under Low oxygen Level

Katja Branitzki-Heinemann et al.

FRONTIERS IN IMMUNOLOGY (2016)

Article Cardiac & Cardiovascular Systems

Neutrophil extracellular traps in ischemia-reperfusion injury-induced myocardial no-reflow: therapeutic potential of DNase-based reperfusion strategy

Lan Ge et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2015)

Review Endocrinology & Metabolism

Targeting neutrophils in ischemic stroke: translational insights from experimental studies

Glen C. Jickling et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2015)

Review Hematology

Extracellular DNA and histones: double-edged swords in immunothrombosis

T. J. Gould et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2015)

Article Biochemistry & Molecular Biology

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

Huw D. Lewis et al.

NATURE CHEMICAL BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin

Elena Zenaro et al.

NATURE MEDICINE (2015)

Article Biochemistry & Molecular Biology

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

Siu Ling Wong et al.

NATURE MEDICINE (2015)

Article Public, Environmental & Occupational Health

Update on the Global Burden of Ischemic and Hemorrhagic Stroke in 1990-2013: The GBD 2013 Study

Valery L. Feigin et al.

NEUROEPIDEMIOLOGY (2015)

Article Clinical Neurology

Neutrophil recruitment to the brain in mouse and human ischemic stroke

Isabel Perez-de-Puig et al.

ACTA NEUROPATHOLOGICA (2015)

Review Medicine, Research & Experimental

Blood cells and endothelial barrier function

Stephen F. Rodrigues et al.

TISSUE BARRIERS (2015)

Review Biochemistry & Molecular Biology

The Role of Reactive Oxygen Species (ROS) in the Formation of Extracellular Traps (ETs) in Humans

Walter Stoiber et al.

BIOMOLECULES (2015)

Review Hematology

Thrombosis: tangled up in NETs

Kimberly Martinod et al.

Article Endocrinology & Metabolism

Immune cell infiltration in malignant middle cerebral artery infarction: comparison with transient cerebral ischemia

Hannah X. Chu et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2014)

Review Genetics & Heredity

Extracellular histones in tissue injury and inflammation

Ramanjaneyulu Allam et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2014)

Article Multidisciplinary Sciences

Neutrophils scan for activated platelets to initiate inflammation

Vinatha Sreeramkumar et al.

SCIENCE (2014)

Editorial Material Clinical Neurology

Polymorphonuclear neutrophil infiltration into ischemic infarctions: myth or truth?

Hannu Kalimo et al.

ACTA NEUROPATHOLOGICA (2013)

Article Physiology

HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4

Jean-Marc Tadie et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)

Article Biochemistry & Molecular Biology

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones

Colin Longstaff et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Immunology

Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process

Consol Farrera et al.

JOURNAL OF IMMUNOLOGY (2013)

Article Cell Biology

Flavonoids and 5-Aminosalicylic Acid Inhibit the Formation of Neutrophil Extracellular Traps

Tina Kirchner et al.

MEDIATORS OF INFLAMMATION (2013)

Article Multidisciplinary Sciences

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

Kimberly Martinod et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Immunology

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

Marie-Luise von Bruehl et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2012)

Article Biochemistry & Molecular Biology

Singlet oxygen is essential for neutrophil extracellular trap formation

Yoko Nishinaka et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

Article Medical Laboratory Technology

The value of serial plasma nuclear and mitochondrial DNA levels in patients with acute ischemic stroke

Nai-Wen Tsai et al.

CLINICA CHIMICA ACTA (2011)

Article Biochemistry & Molecular Biology

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

Abdul Hakkim et al.

NATURE CHEMICAL BIOLOGY (2011)

Review Biochemistry & Molecular Biology

Intracellular generation of superoxide by the phagocyte NADPH oxidase How, where, and what for?

Johan Bylund et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Article Cell Biology

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

Venizelos Papayannopoulos et al.

JOURNAL OF CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

Steffen Massberg et al.

NATURE MEDICINE (2010)

Article Multidisciplinary Sciences

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

Abdul Hakkim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Extracellular DNA traps promote thrombosis

Tobias A. Fuchs et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Immunology

Neutrophil kinetics in health and disease

Charlotte Summers et al.

TRENDS IN IMMUNOLOGY (2010)

Article Immunology

Activation of the Human Contact System on Neutrophil Extracellular Traps

Sonja Oehmcke et al.

JOURNAL OF INNATE IMMUNITY (2009)

Review Genetics & Heredity

Innate immunity turned inside-out: antimicrobial defense by phagocyte extracellular traps

Maren von Kockritz-Blickwede et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2009)

Article Neurosciences

Neutrophil elastase and neurovascular injury following focal stroke and reperfusion

Ann M. Stowe et al.

NEUROBIOLOGY OF DISEASE (2009)

Article Multidisciplinary Sciences

Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps

Anderson B. Guimaraes-Costa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Immunology

DNase 1 and systemic lupus erythematosus

Fernando Martinez Valle et al.

AUTOIMMUNITY REVIEWS (2008)

Article Immunology

Histone deimination as a response to inflammatory stimuli in neutrophils

Indira Neeli et al.

JOURNAL OF IMMUNOLOGY (2008)

Review Microbiology

Beneficial suicide: why neutrophils die to make NETs

Volker Brinkmann et al.

NATURE REVIEWS MICROBIOLOGY (2007)

Article Cell Biology

Novel cell death program leads to neutrophil extracellular traps

Tobias A. Fuchs et al.

JOURNAL OF CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

Stephen R. Clark et al.

NATURE MEDICINE (2007)

Article Clinical Neurology

Nucleosomes in serum of patients with early cerebral stroke

S Geiger et al.

CEREBROVASCULAR DISEASES (2006)

Article Biochemistry & Molecular Biology

Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation

S Martinelli et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Medical Laboratory Technology

Prognostic use of circulating plasma nucleic acid concentrations in patients with acute stroke

TH Rainer et al.

CLINICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Cathepsin G activates protease-activated receptor-4 in human platelets

GR Sambrano et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)