期刊
MOLECULAR CELL
卷 81, 期 22, 页码 4577-4578出版社
CELL PRESS
DOI: 10.1016/j.molcel.2021.10.021
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资金
- CPRIT [RR190090]
The study by Shi et al. demonstrates that the tumor-suppressive and developmental functions of UTX rely on an intrinsically disordered region (IDR) capable of forming condensates. These findings further support the functional role of IDR-mediated spatial organization in regulating gene expression in development and disease.
Shi et al. (2021) demonstrate that tumor-suppressive and developmental functions of UTX require an intrin-sically disordered region (IDR) capable of condensate formation. These results provide further evidence for the functional role of IDR-mediated spatial organization in regulating gene expression in development and disease.
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