期刊
MICROBIOLOGICAL RESEARCH
卷 252, 期 -, 页码 -出版社
ELSEVIER GMBH
DOI: 10.1016/j.micres.2021.126867
关键词
Antimicrobial activity; Antifungal activity; Methodologies; Laboratory assays; Bacteria; Fungi
类别
Fungal and microbial infections are increasingly common, leading to a growing need for new antifungal and antimicrobial agents. Scientists are searching for new molecules to combat fungal infections, utilizing various methods to determine antimicrobial activity of potential drugs.
Fungal and microbial infections are increasingly common diseases affecting not only humans, but also animals. Despite the fact that there are wide ranges of antifungal drugs that can be used as therapy against different types of mycosis, the large-scale needed for new antifungal and antimicrobial agents is undeniable. The reasons for a great demand for new agents are low effectiveness due to the development of resistance, host toxicity and various side effects of currently used therapeutics. In order to develop novel drugs against fungal infections, scientists need to search for new molecules that show antimicrobial activity. However, there are various methods to determine antifungal and antimicrobial activity such as diffusion methods, bioautography methods, dilution methods and other frequently used methods. This review aims to explain the methodologies mentioned, to highlight the functioning, usage, advantages and disadvantages and to compare the techniques using different sources of the last years. Additionally, some of the currently investigated natural compounds such as essential oils, which show promising results in the medication of fungal diseases, are mentioned.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据