期刊
MATERIALS LETTERS
卷 307, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.matlet.2021.131093
关键词
Biomaterials; Carbon materials; Photosynthetic-bacteria; Green synthesis; Red emissive carbon dots; Lysosomal imaging
资金
- National Natural Science Foundation of China [31770066, 31470218]
- Open Fund for Anhui Key Laboratory of Modern Biomanufacturing of Anhui University
- Key Laboratory of Human Microenvironment and Precision Medicine of Anhui Higher Education Institutes, Anhui University
A novel red emissive carbon dots derived from photosynthetic bacteria were synthesized successfully, exhibiting good water solubility, biocompatibility, and red photoluminescence emission. The CDs showed low toxicity and efficient imaging of cells, mainly lysosomes, making them a potential material for biomedical applications.
A novel red emissive carbon dots (CDs) derived from photosynthetic bacteria are synthesized successfully via a simple microwave-assisted hydrothermal process. The CDs exhibit good water solubility, biocompatibility, and red photoluminescence emission with an absolute quantum yield of 15.17% in water. More importantly, 5 mg/ml CDs present low toxicity after co-cultured with human umbilical vein endothelial cells (HUVECs) and HeLa cells. Furthermore, the red emissive CDs can clearly image the HUVECs and HeLa cells within 10 min and maintain stable emission for 1 h. It is also proved that the organelle of CD imaging is mainly lysosome. This work provides a new method to prepare long-wavelength fluorescence-emission CDs and explores a new material with potential applications in the biomedical field.
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