期刊
LWT-FOOD SCIENCE AND TECHNOLOGY
卷 151, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.lwt.2021.112089
关键词
Principal component analysis; Compound preparation; Response surface methodology; Microemulsion; Natural preservative
资金
- National Key Research and Development Project [2018YFD0800201]
The study extracted essential oils from three Chinese herbal medicines, which showed significant antifungal activity against six pathogens. By using response surface methodology, a compound preparation of essential oils was developed to reduce decay index. Additionally, a microemulsion of the compound preparation was created to improve bioavailability and enhance antifungal activity.
The melting fleshed peach is highly susceptible to infection by pathogenic fungi after harvested. Although synthetic preservatives could effectively reduce the spoilage, they normally will pose a threat to the environment and human health. The essential oils (EOs) was extracted from the three Chinese herbal medicines which were considered as a better natural substitute in the application of antifungal substance. Their chemical composition was analyzed by gas chromatography-mass spectrometry (GC-MS), and principal component analysis (PCA) was used to identify possible relationships between EOs composition and habitats. In vitro test, the significantly (P < 0.05) antifungal activity of these EOs against 6 pathogens was proved at 50 mu g/mL dosing concentration. Compound preparation of EOs (CP EOs) significantly (P < 0.001) reduced the decay index based on the optimized composition of three Chinese herbal medicine EOs through response surface methodology (RSM). CP EOs microemulsion (M-CP EOs) was developed to improve the bioavailability, which could significantly (P < 0.05) increase the antifungal activity compared with CP EOs. Consequently, these EOs could be considered for the production of natural preservative which reduced our dependence on the synthetic preservatives.
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