4.5 Article

Hearing Loss and Its Burden of Disease in a Large German Cohort-Hearing Loss in Germany

期刊

LARYNGOSCOPE
卷 132, 期 9, 页码 1843-1849

出版社

WILEY
DOI: 10.1002/lary.29980

关键词

Cohort study; hearing loss; audiology; otology; neurotology

资金

  1. government of Rhineland-Palatinate (Stiftung Rheinland-Pfalz fur Innovation [AZ 961-386261/733]
  2. Johannes Gutenberg-University of Mainz
  3. Boehringer Ingelheim
  4. PHILIPS Medical Systems
  5. Federal Ministry of Education and Research [BMBF 01EO1503]

向作者/读者索取更多资源

The study aimed to estimate the burden of hearing loss in a large German cohort, with 40.9% of the population affected. Understanding the impact of hearing loss will provide the foundation for future patient care guidelines.
Objectives/Hypothesis Hearing loss is the most common sensory impairment worldwide. It restricts patients in many aspects of their daily lives and can lead to social exclusion. Understanding this burden is a mandatory requirement for the care of those affected. Therefore, the aim of this study was to estimate the burden of hearing loss in a large German cohort. Study Design Cohort study. Methods The Gutenberg Health Study is designed as a single-center, prospective, and observational cohort study and representative for the city of Mainz, Germany, with its district. Participants were interviewed concerning common otologic symptoms and tested by pure-tone audiometry. The primary outcome was hearing impairment stratified by age and sex. The prevalence of tinnitus was estimated for a subcohort to calculate disability-adjusted life years (DALYs). All results were weighted by the European Standard Population (ESP) 2013. Results A total of 5,024 participants (mean age: 61.2 years, 2,591 men and 2,433 women) were included in the study. Hearing impairment showed the following prevalence: 28.2% (95% confidence interval [CI], 26.9%-29.4%) mild impairment, 10.1% (95% CI, 9.3%-11.0%) moderate impairment, 2.3% (95% CI, 1.9%-2.7%) moderately severe impairment, 0.2% (95% CI, 0.1%-0.4%) severe impairment, 0% (95% CI, 0.0%-0.1%) profound impairment, and 0.1% (95% CI, 0.0%-0.2%) complete impairment. Weighted for the ESP 2013 (all ages), hearing impairment across all levels (with/without tinnitus) causes a total of 2,118.97 DALYs per 100,000. Conclusion With 40.9% affected, the hearing loss represents a relevant burden of the German population. Understanding this will provide the basis for future guidelines on how to care for these patients. Level of Evidence 2 Laryngoscope, 2021

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