☆ 4.8 Letter

Breakthrough infections with SARS-CoV-2 omicron despite mRNA vaccine booster dose

LANCET (2022)

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

Sandile Cele et al.

Summary: The study found that the Omicron variant has reduced neutralizing effectiveness in individuals vaccinated with Pfizer BNT162b2, but those who had previously been infected with SARS-CoV-2 showed better neutralization against Omicron.

NATURE (2022)

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Article Microbiology

Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant-dependent manner

Roanne Keeton et al.

Summary: The study shows that vaccination with Ad26.COV2.S after infection can significantly enhance protection against COVID-19, especially against different virus variants. In addition, the vaccine also induces robust CD4 and CD8 T cell responses, regardless of prior infection.

CELL HOST & MICROBE (2021)

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Article Multidisciplinary Sciences