Few young athletes meet newly derived age- and activity-relevant functional recovery targets after ACL reconstruction

Purpose National registry data have established Knee injury and Osteoarthritis Outcome Score (KOOS) functional recovery target values for adults after anterior cruciate ligament (ACL) reconstruction. However, the specificity of these target values for young athletes after ACL reconstruction is unclear. The purpose of this analysis was to (1) derive age- and activity-relevant KOOS functional recovery target values from uninjured young athlete data and (2) determine clinical measures at the time of RTS clearance associated with meeting the newly-derived functional recovery target values in young athletes following ACLR. Methods Two hundred and twenty-two young athletes (56 uninjured controls, 17.2 +/- 2.4 years, 73% female; 166 after ACL reconstruction, 16.9 +/- 2.2 years, 68% female) were included in this cross-sectional analysis from a larger cohort study. Uninjured control participants completed the KOOS, and functional recovery target values were defined as the lower bound of the 95% confidence interval for KOOS subscales. ACL reconstruction participants completed testing within 4 weeks of return-to-sport clearance, including the KOOS, single-leg hop tests, and isometric quadriceps strength. In ACL reconstruction participants, logistic regression was used to determine predictors of meeting all KOOS functional recovery target values (primary outcome) among demographic/injury, hop, and strength data (alpha <= 0.05). Results KOOS functional recovery target values for each subscale from uninjured athlete data were: Pain >= 94, Symptoms >= 92, Activities of Daily Living >= 97, Sport >= 92, and Quality-of-Life >= 92. At the time of return-to-sport clearance, ACL reconstruction participants met the KOOS functional recovery targets in the following proportions: Pain, 63%; Symptoms, 42%; Activities of Daily Living, 80%; Sport, 45%; Quality-of-Life, 24%; overall functional recovery (met all subscale targets), 17%. In ACL reconstruction participants, significant predictors of overall functional recovery (primary outcome) were: younger age, hamstring graft, pediatric ACL reconstruction, quadriceps strength limb-symmetry index > 90%, single-hop limb-symmetry index > 90%, and crossover-hop limb-symmetry index > 90%. Conclusions KOOS functional recovery target values derived from uninjured young athletes were higher than those previously reported. Small proportions of young athletes following recent RTS clearance after ACLR met these newly-derived functional recovery target values, and factors associated with meeting functional recovery target values included younger age, hamstring autograft and pediatric ACLR, and having > 90% LSI for quadriceps strength and single-leg hop tests.

Automated summary

Functional recovery target values derived from uninjured young athletes were higher than previously reported. Only small proportions of young athletes following recent return-to-sport clearance after ACL reconstruction met these newly-derived functional recovery target values, with factors associated with meeting them including younger age, hamstring autograft and pediatric ACL reconstruction, and having > 90% limb-symmetry index for quadriceps strength and single-leg hop tests.