Can melatonin be used as a potential antioxidant and sleep aid supplement for high-altitude travelers?

Article Biology

Melatonin supplementation improves psychomotor and physical performance in collegiate student-athletes following a sleep deprivation night

Nesa Paryab et al.

Summary: Studies show that melatonin supplementation can have positive effects on psychomotor performance and physical fitness measures of collegiate student-athletes, especially after sleep deprivation. However, the ingestion of melatonin had no significant effect on dependent variables in student-athletes without sleep deprivation.

CHRONOBIOLOGY INTERNATIONAL (2021)

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Review Nutrition & Dietetics

Does Evidence Exist to Blunt Inflammatory Response by Nutraceutical Supplementation during COVID-19 Pandemic? An Overview of Systematic Reviews of Vitamin D, Vitamin C, Melatonin, and Zinc

Salvatore Corrao et al.

Summary: COVID-19 has become a major global public health challenge with no proven specific antiviral drugs currently available. Nutraceutical supplements such as vitamin D, vitamin C, melatonin, and zinc may have some impact on the inflammatory state and immune system function of patients, potentially offering a strategy to mitigate the worst outcomes of the pandemic.

NUTRIENTS (2021)

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Review Nutrition & Dietetics

Efficacy of Functional Foods, Beverages, and Supplements Claiming to Alleviate Air Travel Symptoms: Systematic Review and Meta-Analysis

Virginia Chan et al.

Summary: This study evaluated the efficacy of functional foods, beverages, and supplements claiming to address the effects of air travel for healthy adults. Melatonin was found to reduce self-reported jetlag after eastbound and westbound flights, while Pycnogenol showed effectiveness in reducing edema scores. Overall, only 12 out of 183 ingredients contained in 199 products had evidence to support their claims.

NUTRIENTS (2021)

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Review Pharmacology & Pharmacy