4.5 Article

Molecular characterization of Schistosoma infections in African migrants: identification of a Schistosoma haematobium-bovis hybrid in bladder biopsies

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JOURNAL OF TRAVEL MEDICINE
卷 29, 期 7, 页码 -

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OXFORD UNIV PRESS INC
DOI: 10.1093/jtm/taab194

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ITS2; cox1; Schistosoma hybrid; phylogenetic analysis

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This text discusses the discovery of atypical Schistosoma haematobium eggs in a bladder biopsy from an African migrant with severe Schistosomiasis, and the identification of a S. haematobium-Schistosoma bovis hybrid through mitochondrial and genomic DNA amplification. Phylogenetic analysis grouped this hybrid sequence with others from western Africa.
Atypical Schistosoma haematobium eggs were found in a bladder biopsy from an African migrant with severe Schistosomiasis. Amplification of mitochondrial (cox 1) and genomic (ITS2) DNA identified the presence of a S. haematobium-Schistosoma bovis hybrid. Phylogenetic analysis clustered the hybrid sequence with other sequences from western Africa.

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