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Small Cell Lung Cancer, Version 2.2022

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HARBORSIDE PRESS
DOI: 10.6004/jnccn.2021.0058

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The NCCN Clinical Practice Guidelines in Oncology provide recommendations for the management of SCLC, emphasizing the importance of systemic therapy for extensive-stage disease and promoting smoking cessation in patients.
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Small Cell Lung Cancer (SCLC) provide recommended management for patients with SCLC, including diagnosis, primary treatment, surveillance for relapse, and subsequent treatment. This selection for the journal focuses on metastatic (known as extensive stage) SCLC, which is more common than limited-stage SCLC. Systemic therapy alone can palliate symptoms and prolong survival in most patients with extensive-stage disease. Smoking cessation counseling and intervention should be strongly promoted in patients with SCLC and other high-grade neuroendocrine carcinomas. The Summary of the Guidelines Updates section in the SCLC algorithm outlines the most recent revisions for the 2022 update, which are described in greater detail in this revised Discussion text.

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