期刊
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
卷 78, 期 25, 页码 2573-2579出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jacc.2021.10.020
关键词
ethnic disparities; heart failure; hypertrophic cardiomyopathy; race disparities; social determinants
资金
- South African Medical Research Council (SA-MRC)
- MRC UK
- National Research Foundation
- Lily and Ernst Hausmann Trust
- Hippocrates Foundation
- South African Medical Research Council
Significant racial and ethnicity-based disparities exist in the clinical presentation, management, and outcome of hypertrophic cardiomyopathy (HCM). Black patients with HCM are more likely to present with heart failure, and they have lower survival rates.
Significant racial and ethnicity-based disparities in clinical presentation, management, and outcome of hypertrophic cardiomyopathy (HCM) are reported. Black patients with HCM are more likely to present with heart failure but are less commonly referred for symptom management, sudden cardiac death stratification, surgical septal myectomy, or for implantable cardioverter-defibrillators, all interventions that increase survival. Prevalence of bystander cardiopulmonary resuscitation is lower for Black patients than for White patients. Black patients with HCM have decreased survival after hospital discharge following out-of-hospital cardiac arrest. Biomedical and social interventions are urgently needed to reduce ethnicity-based disparities, which have an impact on outcomes in HCM and other cardiovascular diseases. There is also a need to focus on implementation science to support durable adoption of evidence-based therapies in Black patients and communities. (C) 2021 by the American College of Cardiology Foundation.
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