4.8 Article

Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations

Sneha Rath et al.

Summary: MitoCarta3.0 is a catalog of over 1000 genes encoding the mammalian mitochondrial proteome, with 1136 human genes after manual review. It includes annotations of sub-mitochondrial localization and hierarchical 'MitoPathways', serving as a valuable resource for mitochondrial biology and medicine.

NUCLEIC ACIDS RESEARCH (2021)

Article Biochemistry & Molecular Biology

Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1

Hye-Kyung Park et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2020)

Article Multidisciplinary Sciences

General and robust covalently linked graphene oxide affinity grids for high-resolution cryo-EM

Feng Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Cell Biology

Structure, Function, and Regulation of the Hsp90 Machinery

Maximilian M. Biebl et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2019)

Review Cell Biology

The HSP90 chaperone machinery

Florian H. Schopf et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Review Chemistry, Medicinal

Paralog Specific Hsp90 Inhibitors - A Brief History and a Bright Future

Daniel T. Gewirth

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2016)

Article Medicine, Research & Experimental

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis

Yan Xiang et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Article Chemistry, Multidisciplinary

Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1

Chang-Wook Lee et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Editorial Material Oncology

Stressing the Development of Small Molecules Targeting HSP90

Len Neckers et al.

CLINICAL CANCER RESEARCH (2014)

Review Cell Biology

Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells

Andrea Rasola et al.

TRENDS IN CELL BIOLOGY (2014)

Review Oncology

Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?

Simran S. Sabharwal et al.

NATURE REVIEWS CANCER (2014)

Article Multidisciplinary Sciences

Landscape of the mitochondrial Hsp90 metabolome in tumours

Young Chan Chae et al.

NATURE COMMUNICATIONS (2013)

Article Oncology

Evidence for Efficacy of New Hsp90 Inhibitors Revealed by Ex Vivo Culture of Human Prostate Tumors

Margaret M. Centenera et al.

CLINICAL CANCER RESEARCH (2012)

Article Biochemistry & Molecular Biology

Ribosomal protein L2 associates with E. coli HtpG and activates its ATPase activity

Yuko Motojima-Miyazaki et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)

Article Multidisciplinary Sciences

Protein-binding assays in biological liquids using microscale thermophoresis

Christoph J. Wienken et al.

NATURE COMMUNICATIONS (2010)

Review Oncology

Targeting the dynamic HSP90 complex in cancer

Jane Trepel et al.

NATURE REVIEWS CANCER (2010)

Article Medicine, Research & Experimental

Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90

Byoung Heon Kang et al.

JOURNAL OF CLINICAL INVESTIGATION (2009)

Review Biochemistry & Molecular Biology

Compartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones

B. H. Kang et al.

ONCOGENE (2009)

Article Biochemistry & Molecular Biology

Stimulation of the weak ATPase activity of human Hsp90 by a client protein

SH McLaughlin et al.

JOURNAL OF MOLECULAR BIOLOGY (2002)

Review Biochemistry & Molecular Biology

GHKL, an emergent ATPase/kinase superfamily

R Dutta et al.

TRENDS IN BIOCHEMICAL SCIENCES (2000)