期刊
JOURNAL OF PHYSICS D-APPLIED PHYSICS
卷 55, 期 20, 页码 -出版社
IOP Publishing Ltd
DOI: 10.1088/1361-6463/ac526d
关键词
magnetic nanoparticles; magnetic hyperthermia; magnetic fluid hyperthermia; focused heating; targeted therapy
资金
- CNR/MTA Italy-Hungary 2019-2021 Joint Project 'Strongly interacting systems in confined geometries'
- COST 'European network for advancing electromagnetic hyperthermic medical technologies' [CA17115]
- Hungarian National Research, Development and Innovation Office (NKFIH) [K137852]
- Quantum Information National Laboratory - Ministry of Innovation and Technology via the NKFIH
Magnetic hyperthermia is an adjuvant therapy that uses magnetic nanoparticles to transfer energy and increase the local temperature of the human body. The combination of static and alternating magnetic fields can enhance this localization effect. Research shows a significant polarization effect in superlocalization for small frequencies and large field strengths, which is important for practical applications.
Magnetic hyperthermia is an adjuvant therapy for cancer where injected magnetic nanoparticles are used to transfer energy from the time-dependent applied magnetic field into the surrounding medium. Its main importance is to be able to increase the temperature of the human body locally. This localization can be further increased by using a combination of static and alternating external magnetic fields. For example, if the static field is inhomogeneous and the alternating field is oscillating then the energy transfer and consequently, the heat generation is non-vanishing only where the gradient field is zero, which results in superlocalization. Our goal here is to study theoretically and experimentally whether the perpendicular or parallel combination of static and oscillating fields produce a better superlocalization. A considerable polarization effect in superlocalization for small frequencies and large field strengths is found, which is of great importance for practical applications.
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