期刊
JOURNAL OF PHARMACY AND PHARMACOLOGY
卷 74, 期 5, 页码 681-710出版社
OXFORD UNIV PRESS
DOI: 10.1093/jpp/rgab098
关键词
Azadirachta indica; diabetic complications; oxidative stress; carbohydrate digestive enzymes; glucose uptake
资金
- JSS AHER
The research provides a critical review on the pharmacological activities and phytochemistry of Azadirachta indica related to diabetes management, showing its potential as an antidiabetic herbal medicine. However, gaps in research indicate a need for further systematic evaluation.
Objective We aim to provide a critical review focused on the various pharmacological activities of Azadirachta indica A. Juss related to diabetes management. We also emphasise on phytochemistry and toxicology of A. indica, which could provide a comprehensive approach for plant-based drug development in future. Key findings From 2784 identified studies, only 83 were considered after double screening based on the inclusion criteria. Further, 63 pharmacological investigations were considered for review. Resultant studies deliberated on using different extracts and phytochemicals of A. indica on blood glucose level, lipid profile, oxidative stress, carbohydrate digestion enzymes, diabetic complications, glucose tolerance, and uptake of glucose. In the end, one can know the efficacy of A. indica as a potent antidiabetic herbal medicine. However, based on gaps in research, recommendations have been provided to evaluate A. indica. in a systematic manner to develop plant-based drugs, nutraceuticals, and to evaluate their clinical efficiency and safety against diabetes mellitus.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据