相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Monitoring of the sedimentation kinetics of vaccine adjuvants using water proton NMR relaxation
Marc B. Taraban et al.
MAGNETIC RESONANCE IN CHEMISTRY (2021)
Raman spectroscopy as process analytical tool in downstream processing of biotechnology
Yu Kiat Lin et al.
CHINESE JOURNAL OF CHEMICAL ENGINEERING (2021)
Real-time bioprocess monitoring using a mid-infrared fibre-optic sensor
Farah Alimagham et al.
BIOCHEMICAL ENGINEERING JOURNAL (2021)
Production of high-quality SARS-CoV-2 antigens: Impact of bioprocess and storage on glycosylation, biophysical attributes, and ELISA serologic tests performance
Rute Castro et al.
BIOTECHNOLOGY AND BIOENGINEERING (2021)
A genome-scale metabolic network model and machine learning predict amino acid concentrations in Chinese Hamster Ovary cell cultures
Song-Min Schinn et al.
BIOTECHNOLOGY AND BIOENGINEERING (2021)
Monitoring E. coli Cell Integrity by ATR-FTIR Spectroscopy and Chemometrics: Opportunities and Caveats
Jens Kastenhofer et al.
PROCESSES (2021)
Process Analytical Technology for Precipitation Process Integration into Biologics Manufacturing towards Autonomous Operation-mAb Case Study
Lara Julia Lohmann et al.
PROCESSES (2021)
Viable cell density on-line auto-control in perfusion cell culture aided by in-situ Raman spectroscopy
Gong Chen et al.
BIOCHEMICAL ENGINEERING JOURNAL (2021)
How to draw the line - Raman spectroscopy as a tool for the assessment of biomedicines
Christel Kamp et al.
BIOLOGICAL CHEMISTRY (2021)
PAT solutions to monitor adsorption of Tetanus Toxoid with aluminum adjuvants
Manjit Haer et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2021)
Digital Twin of mRNA-Based SARS-COVID-19 Vaccine Manufacturing towards Autonomous Operation for Improvements in Speed, Scale, Robustness, Flexibility and Real-Time Release Testing
Axel Schmidt et al.
PROCESSES (2021)
Moving towards an era of hybrid modelling: advantages and challenges of coupling mechanistic and data-driven models for upstream pharmaceutical bioprocesses
Apostolos Tsopanoglou et al.
CURRENT OPINION IN CHEMICAL ENGINEERING (2021)
In-line monitoring of surfactant clearance in viral vaccine downstream processing
Jessie Payne et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2021)
Structure and compositional analysis of aluminum oxyhydroxide adsorbed pertussis vaccine
Jessica Duprez et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2021)
Automatic real-time calibration, assessment, and maintenance of generic Raman models for online monitoring of cell culture processes
Aditya Tulsyan et al.
BIOTECHNOLOGY AND BIOENGINEERING (2020)
Current and future requirements to industrial analytical infrastructure-part 2: smart sensors
Tobias Eifert et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2020)
Real-time benchtop NMR spectroscopy for the online monitoring of sucrose hydrolysis
Alper Soyler et al.
LWT-FOOD SCIENCE AND TECHNOLOGY (2020)
Quality assurance at the point-of-care: Noninvasively detecting vaccine freezing variability using water proton NMR
Katharine T. Briggs et al.
VACCINE (2020)
Technology outlook for real-time quality attribute and process parameter monitoring in biopharmaceutical development-A review
Dhanuka P. Wasalathanthri et al.
BIOTECHNOLOGY AND BIOENGINEERING (2020)
Real-time monitoring of quality attributes by in-line Fourier transform infrared spectroscopic sensors at ultrafiltration and diafiltration of bioprocess
Dhanuka P. Wasalathanthri et al.
BIOTECHNOLOGY AND BIOENGINEERING (2020)
Analysis of Transformed Upstream Bioprocess Data Provides Insights into Biological System Variation
Anne Richelle et al.
BIOTECHNOLOGY JOURNAL (2020)
Enzyme capacity-based genome scale modelling of CHO cells
Hock Chuan Yeo et al.
METABOLIC ENGINEERING (2020)
Using benchtop NMR spectroscopy as an online non-invasive in vivo lipid sensor for microalgae cultivated in photobioreactors
Dylan Bouillaud et al.
PROCESS BIOCHEMISTRY (2020)
An Artificial Neural Network Assisted Dynamic Light Scattering Procedure for Assessing Living Cells Size in Suspension
Dan Chicea
SENSORS (2020)
Towards a Digital Bioprocess Replica: Computational Approaches in Biopharmaceutical Development and Manufacturing
Jens Smiatek et al.
TRENDS IN BIOTECHNOLOGY (2020)
Digital Twins in Pharmaceutical and Biopharmaceutical Manufacturing: A Literature Review
Yingjie Chen et al.
PROCESSES (2020)
Flexible automation with compact NMR spectroscopy for continuous production of pharmaceuticals
Simon Kern et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2019)
Kinetics of Asymmetric Transfer Hydrogenation, Catalyst Deactivation, and Inhibition with Noyori Complexes As Revealed by Real-Time High-Resolution FIowNMR Spectroscopy
Andrew M. R. Hall et al.
ACS CATALYSIS (2019)
The application of process analytical technologies (PAT) to the dairy industry for real time product characterization - process viscometry
Norah O'Shea et al.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2019)
Data science tools and applications on the way to Pharma 4.0
Valentin Steinwandter et al.
DRUG DISCOVERY TODAY (2019)
Benchtop NMR for the monitoring of bioprocesses
Dylan Bouillaud et al.
MAGNETIC RESONANCE IN CHEMISTRY (2019)
Identity, Structure and Compositional Analysis of Aluminum Phosphate Adsorbed Pediatric Quadrivalent and Pentavalent Vaccines
Kristen Kalbfleisch et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2019)
Aluminum Phosphate Vaccine Adjuvant: Analysis of Composition and Size Using Off-Line and In-Line Tools
Carmen Mei et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2019)
In-line monitoring of amino acids in mammalian cell cultures using raman spectroscopy and multivariate chemometrics models
Hemlata Bhatia et al.
ENGINEERING IN LIFE SCIENCES (2018)
Role of raw materials in biopharmaceutical manufacturing: risk analysis and fingerprinting
Anurag S. Rathore et al.
CURRENT OPINION IN BIOTECHNOLOGY (2018)
27Al and 31P NMR spectroscopy method development to quantify aluminum phosphate in adjuvanted vaccine formulations
Rahima Khatun et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2018)
Raman spectroscopy-based identification of toxoid vaccine products
Anja Silge et al.
NPJ VACCINES (2018)
Understanding modern-day vaccines: what you need to know
Volker Vetter et al.
ANNALS OF MEDICINE (2018)
Spectroscopic sensors for in-line bioprocess monitoring in research and pharmaceutical industrial application
Jens Classen et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2017)
On-line prediction of the glucose concentration of CHO cell cultivations by NIR and Raman spectroscopy: Comparative scalability test with a shake flask model system
Bence Kozma et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2017)
Real-time product release and process control challenges in the dairy milk powder industry
Muhammad Tajammal Munir et al.
CURRENT OPINION IN FOOD SCIENCE (2017)
Reaction monitoring using online vs tube NMR spectroscopy: seriously different results
David A. Foley et al.
MAGNETIC RESONANCE IN CHEMISTRY (2016)
Closed Loop Control of Lactate Concentration in Mammalian Cell Culture by Raman Spectroscopy Leads to Improved Cell Density, Viability, and Biopharmaceutical Protein Production
Thomas E. Matthews et al.
BIOTECHNOLOGY AND BIOENGINEERING (2016)
Online monitoring of fermentation processes via non-invasive low-field NMR
Dirk Kreyenschulte et al.
BIOTECHNOLOGY AND BIOENGINEERING (2015)
Sensor systems for bioprocess monitoring
Philipp Biechele et al.
ENGINEERING IN LIFE SCIENCES (2015)
Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review
Levente L. Simon et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2015)
NMR Flow Tube for Online NMR Reaction Monitoring
David A. Foley et al.
ANALYTICAL CHEMISTRY (2014)
Chemometrics and in-line near infrared spectroscopic monitoring of a biopharmaceutical Chinese hamster ovary cell culture: Prediction of multiple cultivation variables
Matthieu Clavaud et al.
TALANTA (2013)
Single-use disposable technologies for biopharmaceutical manufacturing
Abhinav A. Shukla et al.
TRENDS IN BIOTECHNOLOGY (2013)
Bioreactor monitoring with spectroscopy and chemometrics: a review
N. D. Lourenco et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2012)
In situ Raman spectroscopy for simultaneous monitoring of multiple process parameters in mammalian cell culture bioreactors
Jessica Whelan et al.
BIOTECHNOLOGY PROGRESS (2012)
Real Time Monitoring of Multiple Parameters in Mammalian Cell Culture Bioreactors Using an In-Line Raman Spectroscopy Probe
Nicholas R. Abu-Absi et al.
BIOTECHNOLOGY AND BIOENGINEERING (2011)
Near infrared and Raman spectroscopy for the in-process monitoring of pharmaceutical production processes
T. De Beer et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2011)
Influence of Protein Conformation and Adjuvant Aggregation on the Effectiveness of Aluminum Hydroxide Adjuvant in a Model Alkaline Phosphatase Vaccine
Amber L. Clausi et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
The Process Development of Ravuconazole: An Efficient Multikilogram Scale Preparation of an Antifungal Agent
Jaan Pesti et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2009)
Inhibition of aggregation of aluminum hydroxide adjuvant during freezing and drying
Amber L. Clausi et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Near-infrared spectroscopy and imaging: Basic principles and pharmaceutical applications
G Reich
ADVANCED DRUG DELIVERY REVIEWS (2005)
On-line multi-analyzer monitoring of biomass, glucose and acetate for growth rate control of a Vibrio cholerae fed-batch cultivation
M Navrátil et al.
JOURNAL OF BIOTECHNOLOGY (2005)