Low In-School COVID-19 Transmission and Asymptomatic Infection Despite High Community Prevalence

Article Immunology

Comparing Nasopharyngeal Swab and Early Morning Saliva for the Identification of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Mohan Rao et al.

Summary: This study shows that saliva is a better alternative specimen for detecting SARS-CoV-2. The detection rate of SARS-CoV-2 was higher in saliva compared to NPS, and saliva collection is simple and can reduce exposure to healthcare workers.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Immunology

Reopening Schools and the Dynamics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infections in Israel: A Nationwide Study

Ido Somekh et al.

Summary: The study found that reopening of schools led to a gradual increase in SARS-CoV-2 infections in all age groups, with adults showing a significantly higher increase than children. On the other hand, easing restrictions on large-scale gatherings resulted in increased infection and positivity rates for all age groups, as well as higher hospitalizations and mortality.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Infectious Diseases

Minimal transmission of SARS-CoV-2 from paediatric COVID-19 cases in primary schools, Norway, August to November 2020

Lin T. Brandal et al.

Summary: A study in Norwegian primary schools found minimal child-to-child and child-to-adult transmission of SARS-CoV-2 with preventive measures in place, supporting the idea that children under 14 are not the main drivers of virus transmission.

EUROSURVEILLANCE (2021)

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Article Infectious Diseases

SARS-CoV-2 infection and transmission in educational settings: a prospective, cross-sectional analysis of infection clusters and outbreaks in England

Sharif A. Ismail et al.

Summary: This study estimated the rate of SARS-CoV-2 infection and outbreaks among staff and students in educational settings in England during the summer half-term of 2020, finding that infections and outbreaks were uncommon in educational settings, but strongly associated with regional COVID-19 incidence. The results emphasize the importance of controlling community transmission to protect educational settings, with interventions focusing on reducing transmission among staff.

LANCET INFECTIOUS DISEASES (2021)

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Letter Medicine, General & Internal

Open Schools, Covid-19, and Child and Teacher Morbidity in Sweden

Jonas F. Ludvigsson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Pediatrics

Incidence and Secondary Transmission of SARS-CoV-2 Infections in Schools

Kanecia O. Zimmerman et al.

Summary: The study found extremely limited within-school secondary transmission of SARS-CoV-2 during the first 9 weeks of in-person instruction in North Carolina schools, as determined by contact tracing.

PEDIATRICS (2021)

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Article Pediatrics

Prevalence of SARS-CoV-2 Infection in Children and Their Parents in Southwest Germany

Burkhard Toenshoff et al.

Summary: A study conducted in southwest Germany showed that the rate of SARS-CoV-2 infections was low among children aged 1 to 10, suggesting that they are unlikely to have significantly contributed to the pandemic. Large-scale testing provides a basis for informed political decision-making during a pandemic.

JAMA PEDIATRICS (2021)

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Article Public, Environmental & Occupational Health

COVID-19 Cases and Transmission in 17 K–12 Schools — Wood County, Wisconsin, August 31–November 29, 2020

Amy Falk et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

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Review Microbiology

Performance of Saliva, Oropharyngeal Swabs, and Nasal Swabs for SARS-CoV-2 Molecular Detection: a Systematic Review and Meta-analysis

Rose A. Lee et al.

Summary: Nasopharyngeal (NP) swabs are considered the best sample for diagnosing SARS-CoV-2, but saliva, oropharyngeal (OP), nasal (NS) swabs, and combinations of OP/NS are promising alternatives. While some alternative samples had lower detection rates, a combination of OP/NS showed comparable performance to NP swabs. The absence of RNA extraction (saliva) and use of a more sensitive nucleic acid amplification test (NS) significantly reduced the positive yield of alternative samples.

JOURNAL OF CLINICAL MICROBIOLOGY (2021)

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Letter Dentistry, Oral Surgery & Medicine