ZnBr2-Catalyzed Dehydrogenative Borylation of Terminal Alkynes

The simple, commercially available ZnBr2 has been successfully employed as a highly efficient and chemoselective catalyst for the dehydrogenative borylation of terminal alkynes with HBpin under mild conditions. It shows a good tolerance toward various functional groups such as aryl, alkyl, heteroaryl, etc. The plausible reaction mechanism has been investigated based on the corresponding stoichiometric experiments and DFT calculations.

Automated summary

ZnBr2 has been successfully used as a highly efficient and selective catalyst for dehydrogenative borylation of terminal alkynes, showing good tolerance towards various functional groups. The plausible reaction mechanism has been investigated through stoichiometric experiments and DFT calculations.