相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。APCloss induces Warburg effect via increasedPKM2transcription in colorectal cancer
Pu-Hyeon Cha et al.
BRITISH JOURNAL OF CANCER (2021)
Diethyldithiocarbamate-copper complex (CuET) inhibits colorectal cancer progression via miR-16-5p and 15b-5p/ALDH1A3/PKM2 axis-mediated aerobic glycolysis pathway
Xin Huang et al.
ONCOGENESIS (2021)
Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review
Leah H. Biller et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)
Pyruvate kinase M2 (PKM2) in cancer and cancer therapeutics
Susi Zhu et al.
CANCER LETTERS (2021)
PKM2 regulates angiogenesis of VR-EPCs through modulating glycolysis, mitochondrial fission, and fusion
Ranyue Ren et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2020)
Identification of Parthenolide Dimers as Activators of Pyruvate Kinase M2 in Xenografts of Glioblastoma Multiforme in Vivo
Yahui Ding et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment
Pei-pei Hou et al.
MOLECULAR CELL (2020)
Design and SAR of Withangulatin A Analogues that Act as Covalent TrxR Inhibitors through the Michael Addition Reaction Showing Potential in Cancer Treatment
Cheng Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
The Warburg Effect 97 Years after Its Discovery
Rosa Maria Pascale et al.
CANCERS (2020)
Advances in chemistry and bioactivity of parthenolide
Robert R. A. Freund et al.
NATURAL PRODUCT REPORTS (2020)
Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA
Ikuko Nagasawa et al.
CELL CHEMICAL BIOLOGY (2020)
Synthesis and structure-activity relationship studies of parthenolide derivatives as potential anti-triple negative breast cancer agents
Weizhi Ge et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Breaking Glucose Transporter 1/Pyruvate Kinase M2 Glycolytic Loop Is Required for Cantharidin Inhibition of Metastasis in Highly Metastatic Breast Cancer
Yanhong Pan et al.
FRONTIERS IN PHARMACOLOGY (2019)
Development of Novel Irreversible Pyruvate Kinase M2 Inhibitors
I-Shan Hsieh et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Metastatic Colorectal Cancer Rewrites Metabolic Program Through a Glut3-YAP-dependent Signaling Circuit
Chih-Chia Kuo et al.
THERANOSTICS (2019)
Oncogenic Kinase-Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem-like Cells
Zhifen Zhou et al.
CANCER RESEARCH (2018)
Stacking Interactions of Heterocyclic Drug Fragments with Protein Amide Backbones
Andrea N. Bootsma et al.
CHEMMEDCHEM (2018)
LncRNA-FEZFl-AS1 Promotes Tumor Proliferation and Metastasis in Colorectal Cancer by Regulating PKM2 Signaling
Zehua Bian et al.
CLINICAL CANCER RESEARCH (2018)
Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer
Yue Hu et al.
CLINICAL EPIGENETICS (2018)
Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2
Ji Liang et al.
CELL RESEARCH (2017)
Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells
Shobanbabu Bommagani et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Synthesis and anti-acute myeloid leukemia activity of C-14 modified parthenolide derivatives
Zhongjin Yang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
A Blueprint to Advance Colorectal Cancer Immunotherapies
Dung T. Le et al.
CANCER IMMUNOLOGY RESEARCH (2017)
Regulation of EMT in Colorectal Cancer: A Culprit in Metastasis
Trung Vu et al.
CANCERS (2017)
Effects of PKM2 Gene Silencing on the Proliferation and Apoptosis of Colorectal Cancer LS-147T and SW620 Cells
Ran Ao et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)
Synthesis of dual-action parthenolide prodrugs as potent anticancer agents
Akram Taleghani et al.
BIOORGANIC CHEMISTRY (2017)
Chemoenzymatic synthesis and antileukemic activity of novel C9-and C14-functionalized parthenolide analogs
Vikas Tyagi et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2016)
PKM2, cancer metabolism, and the road ahead
Talya L. Dayton et al.
EMBO REPORTS (2016)
Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells
Dongzhu Duan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation
Hugh P. Morgan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Allosteric Regulation of PKM2 Allows Cellular Adaptation to Different Physiological States
Dan Y. Gui et al.
SCIENCE SIGNALING (2013)
Biomimetic Semisynthesis of Arglabin from Parthenolide
Jia-Dai Zhai et al.
JOURNAL OF ORGANIC CHEMISTRY (2012)
Emerging roles of PKM2 in cell metabolism and cancer progression
Weibo Luo et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)
Is there a role for mitomycin C in metastatic colorectal cancer?
Anastasios Dimou et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2010)
β-catenin activates a coordinated expression of the proinvasive factors laminin-5 γ2 chain and MT1-MMP in colorectal carcinomas
F Hlubek et al.
INTERNATIONAL JOURNAL OF CANCER (2004)
Variations in parthenolide content and daily dose of feverfew products
MH Nelson et al.
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2002)
Effects of solvents and water in Ti(III)-mediated radical cyclizations of epoxygermacrolides.: Straightforward synthesis and absolute stereochemistry of (+)-3α-hydroxyreynosin and related eudesmanolides
AF Barrero et al.
JOURNAL OF ORGANIC CHEMISTRY (2002)
分享论文
