A simple and efficient method using aqueous sodium dichloroiodate has been established for the synthesis of alpha-heteroaryl ketones from aryl ketones and amine. This method is mild, operationally simple, with a short reaction time, and yields moderate to good amounts of alpha-N-heteroaryl ketone derivatives.
A simple and efficient method for the synthesis of alpha-heteroaryl ketones from aryl ketones and amine using aqueous sodium dichloroiodate is established. This method is mild, operationally simple, has a short reaction time, and easy workup procedure to afford the corresponding alpha-N-heteroaryl ketone derivatives in moderate to good yield.
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