Phthalate esters in face masks and associated inhalation exposure risk

This study assessed the composition of single-use face mask materials, quantified the concentration of phthalate esters in masks and evaluated associated inhalation exposure risk. All the mask samples, including 12 surgical and four N95/P1/P2 masks, were identified to be made of polypropylene, with polyethylene terephthalate present in the N95/P1/P2 masks. Di-methyl phthalate, di-n-butyl phthalate, di-ethyl phthalate, di-isobutyl phthalate and di(2-ethylhexyl) phthalate were frequently detected and their concentration summed up 55 +/- 35 - 1700 +/- 140 ng per surgical mask and 2300 +/- 150 - 5200 +/- 800 ng per N95/P1/P2 mask. Our simulation experiment suggested a mean loss of 13 - 71% of phthalate mass depending on compounds, during 5-hour wearing of these masks. This resulted in an estimated daily intake of individual compounds no higher than 20 ng/kg/day for adults and 120 ng/kg/day for toddlers, which were at least 80 times lower compared to relevant tolerable daily intake values. Two interventional trials were conducted where a volunteer wore a mask for four hours and urine samples were collected before and after the mask wearing. No obvious increase was observed for the urinary concentration of any phthalate metabolite, indicating minimal contribution to overall exposure to phthalate esters.

Automated summary

This study evaluated the composition of single-use face mask materials, quantified the concentration of phthalate esters in masks, and found that the inhalation exposure risk of phthalate esters from wearing masks is minimal. The study showed that the intake of individual compounds from masks was significantly lower than tolerable daily intake values, and urine samples collected before and after mask wearing did not show a significant increase in phthalate metabolites, indicating minimal contribution to overall exposure.