4.7 Review

Galla Chinensis, a Traditional Chinese Medicine: Comprehensive review of botany, traditional uses, chemical composition, pharmacology and toxicology

期刊

JOURNAL OF ETHNOPHARMACOLOGY
卷 278, 期 -, 页码 -

出版社

ELSEVIER IRELAND LTD
DOI: 10.1016/j.jep.2021.114247

关键词

Galla chinensis; Traditional Chinese medicine; Botany; Ethnopharmacology; Chemical composition; Pharmacology; Toxicology

资金

  1. Xinglin Scholar Scientific Research Promotion Plan for Disciplinary Talents of Chengdu University of Traditional Chinese Medicine, China [QNXZ2018023, XSGG2019008]

向作者/读者索取更多资源

Galla chinensis is a traditional Chinese medicine with diverse pharmacological properties used for over 1400 years. Research has focused on its traditional uses, botanical characteristics, chemical composition, pharmacology, and toxicology, showing potential therapeutic benefits for various diseases. Further studies are needed on the relationship between its components and biological activities, as well as quality control and dynamics of chemical accumulation.
Ethnopharmacological relevance: Galla chinensis (GC), a traditional Chinese medicine (TCM), has a wide range of pharmacological properties which have been widely used for more than 1400 years. Based on shape, GC is divided into two groups: jiaobei and dubei. It is a bitter, sour, cold and astringent substance which is usually used for treating diarrhea, constipation, bleeding, cough, vomiting, sweating, hemorrhoids, and anal and uterine prolapse. It is distributed in Japan, North Korea, and all parts of China. Aim of study: This study was aimed at carrying out a comprehensive overview of the current status of research on Galla chinensis (GC) for better understanding of it characteristics, while providing a clear direction for future studies. It has aroused the interest of researchers, leading to development of medicinal value, expansion of its application, and provision of wider and more effective drug choices. This study was focused on the traditional uses, botany, chemical composition, pharmacology and toxicology of GC. Finally, the study focused on possible future research directions for GC. Materials and methods: A comprehensive analysis was done based on academic papers, pharmaceutical monographs, ancient medicinal works, and drug standards of China. This review used Galla and Galla chinensis as keywords for retrieval of information on GC from online databases such as PubMed, Elsevier, CNKI, Web of Science, Google Scholar, SCI hub, and Baidu academic. Results: It was found that the chemical constituents of GC included tannins, phenolic acid, amino acids and fatty acid, with polyphenol compounds (especially tannins and gallic acid) as the distinct components. In vitro and in vivo studies revealed that GC exerted numerous biological effects such as anti-caries, antibacterial, antiviral, anticancer, and antioxidant effects. The therapeutic effect of GC was attributed mainly to the biological properties of its bioactive components. Conclusions: GC is an important TCM which has potential benefit in the treatment of a variety of diseases. However, the relationship amongst the structure and biological activity of GC and its components, mechanism of action, toxicity, pharmacokinetics and target organs need to be further studied. Quality control and quality assurance programs for GC need to be further developed. There is need to study the dynamics associated with the accumulation of chemical compounds in GC as well as the original plants and aphid that form GC.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据