4.7 Article

An integrated approach to uncover anti-tumor active materials of Curcumae Rhizoma-Sparganii Rhizoma based on spectrum-effect relationship, molecular docking, and ADME evaluation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Oncology

The Role of p53 Signaling in Colorectal Cancer

Magdalena C. Liebl et al.

Summary: The transcription factor p53 is a crucial tumor suppressor that is often mutated or dysregulated in colorectal cancer (CRC), promoting tumorigenesis. Mutations in p53 reduce its tumor suppressor activity and can even provide neo-morphic functions that contribute to cancer development.

CANCERS (2021)

Review Medicine, Research & Experimental

Terpenoids from Curcumae Rhizoma: Their anticancer effects and clinical uses on combination and versus drug therapies

Yi Chen et al.

Summary: Cancer, a fatal disease with no known cure, has prompted research into traditional Chinese medicine for potential anticancer agents. Compounds like beta-elemene from Curcumae Rhizoma have shown promise as potential anticancer drugs, with ongoing clinical trials showing positive results. This review highlights the efficacy of Curcumae Rhizoma and its terpenoids in cancer therapy, offering potential for the development of new anticancer drugs.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Article Mathematical & Computational Biology

Exploring the active constituents of Oroxylum indicum in intervention of novel coronavirus (COVID-19) based on molecular docking method

Sapan Shah et al.

Summary: This study conducted molecular docking research on the main protease (M-pro) responsible for SARS-CoV-2 virus replication, revealing four potential enzyme inhibitors, with Baicalein-7-O-diglucoside and Chrysin-7-O-glucuronide showing the highest binding energy.

NETWORK MODELING AND ANALYSIS IN HEALTH INFORMATICS AND BIOINFORMATICS (2021)

Article Biochemistry & Molecular Biology

RNF115-mediated ubiquitination of p53 regulates lung adenocarcinoma proliferation

Zhigang Luo et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Sesquiterpenes from Curcuma zedoaria rhizomes and their cytotoxicity against human gastric cancer AGS cells

Tae Kyoung Lee et al.

BIOORGANIC CHEMISTRY (2019)

Article Environmental Sciences

Random forest-based estimation of heavy metal concentration in agricultural soils with hyperspectral sensor data

Kun Tan et al.

ENVIRONMENTAL MONITORING AND ASSESSMENT (2019)

Article Biochemical Research Methods

Spectrum-effect relationships between high-performance liquid chromatography fingerprints and anti-inflammatory activities of Leontopodium leontopodioides (Willd.) Beauv.

Yue Zhao et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2019)

Article Oncology

Mutant p53 in Cancer: New Functions and Therapeutic Opportunities

Patricia A. J. Muller et al.

CANCER CELL (2014)

Review Plant Sciences

Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae - A review

Jin-Jian Lu et al.

JOURNAL OF ETHNOPHARMACOLOGY (2012)