4.2 Article

Understanding the excretion rates of methylmercury and inorganic mercury from human body via hair and fingernails

期刊

JOURNAL OF ENVIRONMENTAL SCIENCES
卷 119, 期 -, 页码 59-67

出版社

SCIENCE PRESS
DOI: 10.1016/j.jes.2022.01.041

关键词

Mercury; Methylmercury; Hair; Fingernails; Biomarker; Excretion rate

资金

  1. Strategic Priority Research Programs of the Chinese Academy of Sciences [XDA20040502]
  2. National Natural Science Foundation of China [41877405, U1612442, U1812403]

向作者/读者索取更多资源

This study compared the differences between hair and fingernails as biomarkers and found that hair is a more sensitive biomarker for assessing human mercury exposure levels. Additionally, the study found that the excretion of mercury through hair is 70 to 226 times higher than through fingernails, indicating the greater importance of hair in the elimination of mercury from the human body.
Effective biomarkers are necessary to better understand the human mercury (Hg) exposure levels. However, mismatched biomarker sampling method causes extra uncertainty in assessing the risk of Hg exposure. To compare the differences between hair and fingernail, and further understand the excretion rates of methylmercury (MeHg) and inorganic mercury (IHg) via hair and fingernails, the total mercury (THg), MeHg, and IHg concentrations in paired hair and fingernail samples were investigated through paired samples collected from two typical mining areas, Wanshan mercury mine area (WMMA) and Hezhang zinc smelting area (HZSA). The positive correlation in THg, MeHg, and IHg concentrations (p <0.01) between hair and fingernail samples indicated that those two biomarkers can be corrected in application of assessing human Hg exposure. Compared to fingernails, the hair was suggested to be a more sensitive biomarker as the concentration of THg, MeHg and IHg were 2 similar to 4 times higher than those in fingernails. Furthermore, the amounts of THg, MeHg, and IHg excreted via hair were 70 similar to 226 times higher than that excreted via fingernails, and the hair plays a more important role than fingernails in the excretion of Hg from human bodies. Present study therefore provides some new insights to better understand the fate of human assimilated Hg. (C) 2022 The Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V.

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