Versatile porous nanomaterials for electrochemiluminescence biosensing: Recent advances and future perspective

Porous nanomaterials have attracted widely attention across several scientific communities due to their high porosity, large specific surface area, and versatile functionality. In electrochemiluminescence (ECL) realm, the pore-rich nanostructures can not only effectively load abundant guest ECL luminophores for signal amplification, but also promote the mass and charge transports between the bulk solution and the electrode surface. Some porous nanomaterials with metal centers even display inherent catalytic capacity to assist coreactant ECL. In this review, the basic synthesis strategies and emerging advanced applications of several porous nanomaterials for ECL biosensing are reviewed in detail including mesoporous silica, porous carbon, metal-organic frameworks, and covalent organic frameworks. The challenges of porous nanomaterials-based ECL systems are finally discussed, and the future perspectives are also anticipated. We hope this review could provide readers with a comprehensive understanding of ECL-related porous materials and new ideas.

Automated summary

Porous nanomaterials have high porosity, large specific surface area, and versatile functionality, making them attractive for electrochemiluminescence (ECL) applications. They can effectively load abundant guest ECL luminophores for signal amplification and promote mass and charge transports. This review discusses the synthesis strategies and applications of various porous nanomaterials in ECL biosensing, while also addressing the challenges and future perspectives of these systems.