Preventing infections caused by carbapenemase-producing bacteria in the intensive care unit- Think about the sink

Objective: Outbreaks caused by carbapenemase-producing bacteria (CPB) are challenging to manage in critical care settings and can be protracted due to inadvertent and ubiquitous ecological niches within the built unit environment, such as handwashing sinks. We discuss evidence from a narrative review on transmission pathways and interventions for critical care practitioners. Methods: A literature review was undertaken using Pubmed, CINAHL and Embase and included outbreaks of CPB, and equivalent bacteria in critical care units, between 1998 and May 2020. Intervention studies targeting elements of sinks that were employed in response to outbreaks in critical care units were included (n = 30). Findings: We found control measures included sink removal, use of physical barriers or design modification to protect patients from sinks, engineering controls to mitigate bacterial dispersal and administrative controls. A multi-disciplinary approach involving practitioners from critical care, infection prevention and control, engineering and other staff, should be involved in ongoing measures and in outbreak control activities. Ascertaining the optimal method to end CPB outbreaks in critical care is challenging due to the lack of prospective studies available. However, the literature suggests that sinks can and do serve as reservoirs of CPB near critically ill patients, and should be considered hazardous, especially when sub-optimally designed or used. (c) 2021 Elsevier Inc. All rights reserved.

Automated summary

The study discusses the challenging management of outbreaks caused by carbapenemase-producing bacteria in critical care settings, highlighting the importance of multidisciplinary teamwork in environmental hygiene maintenance and outbreak control activities. Control measures include design and usage adjustments of sinks, engineering controls to mitigate bacterial dispersal, and administrative controls.