相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles
Uri Elia et al.
ACS NANO (2021)
Preparation of cetyl palmitate-based PEGylated solid lipid nanoparticles by microfluidic technique
Ilaria Arduino et al.
ACTA BIOMATERIALIA (2021)
Ultra-small lipid nanoparticles encapsulating sorafenib and midkine-siRNA selectively-eradicate sorafenib-resistant hepatocellular carcinoma in vivo
Mahmoud A. Younis et al.
JOURNAL OF CONTROLLED RELEASE (2021)
Characterization of Lipid Nanoparticles Containing Ionizable Cationic Lipids Using Design-of-Experiments Approach
Takeshi Terada et al.
LANGMUIR (2021)
One-step non-competitive fluorescence polarization immunoassay based on a Fab fragment for C-reactive protein quantification
Keine Nishiyama et al.
SENSORS AND ACTUATORS B-CHEMICAL (2021)
Ionizable lipid nanoparticles for in utero mRNA delivery
Rachel S. Riley et al.
SCIENCE ADVANCES (2021)
Rapid, sensitive universal paper-based device enhances competitive immunoassays of small molecules
Takeshi Komatsu et al.
ANALYTICA CHIMICA ACTA (2021)
Enhancing gene editing efficiency for cells by CRISPR/Cas9 system-loaded multilayered nanoparticles assembled via microfluidics
Xuanyu Li et al.
CHINESE JOURNAL OF CHEMICAL ENGINEERING (2021)
The effect of different organic solvents in liposome properties produced in a periodic disturbance mixer: Transcutol®, a potential organic solvent replacement
Ruben R. Lopez et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2021)
Lipid nanoparticles loaded with ribonucleoprotein-oligonucleotide complexes synthesized using a microfluidic device exhibit robust genome editing and hepatitis B virus inhibition
Yuichi Suzuki et al.
JOURNAL OF CONTROLLED RELEASE (2021)
Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3
Min Qiu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Apolipoprotein E Binding Drives Structural and Compositional Rearrangement of mRNA-Containing Lipid Nanoparticles
Federica Sebastiani et al.
ACS NANO (2021)
Double flow focusing microfluidic-assisted based preparation of methotrexate-loaded liposomal nanoparticles: Encapsulation efficacy, drug release and stability
Halimeh Aghaei et al.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2021)
mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability
Linde Schoenmaker et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)
Impact of lipid nanoparticle size on mRNA vaccine immunogenicity
Kimberly J. Hassett et al.
JOURNAL OF CONTROLLED RELEASE (2021)
Continuous Production of Lipid Nanoparticles by Ultrasound-Assisted Microfluidic Antisolvent Precipitation
Holger Bolze et al.
CHEMICAL ENGINEERING & TECHNOLOGY (2021)
Parametric Study of the Factors Influencing Liposome Physicochemical Characteristics in a Periodic Disturbance Mixer
Ruben R. Lopez et al.
LANGMUIR (2021)
Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device
Sarah J. Shepherd et al.
NANO LETTERS (2021)
3D micromixer for nanoliposome synthesis: a promising advance in high mass productivity
Priscilla C. O. S. Firmino et al.
LAB ON A CHIP (2021)
One-Step Production Using a Microfluidic Device of Highly Biocompatible Size-Controlled Noncationic Exosome-like Nanoparticles for RNA Delivery
Niko Kimura et al.
ACS APPLIED BIO MATERIALS (2021)
Three-dimensional, symmetrically assembled microfluidic device for lipid nanoparticle production
Niko Kimura et al.
RSC ADVANCES (2021)
Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering
Margaret M. Billingsley et al.
NANO LETTERS (2020)
Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA
Siddharth Patel et al.
NATURE COMMUNICATIONS (2020)
Microfluidic-Based Holonomic Constraints of siRNA in the Kernel of Lipid/Polymer Hybrid Nanoassemblies for Improving Stable and Safe In Vivo Delivery
Wei Wei et al.
ACS APPLIED MATERIALS & INTERFACES (2020)
Microfluidic Shrinking Droplet Concentrator for Analyte Detection and Phase Separation of Protein Solutions
Marie R. G. Kopp et al.
ANALYTICAL CHEMISTRY (2020)
Using microfluidics for scalable manufacturing of nanomedicines from bench to GMP: A case study using protein-loaded liposomes
Cameron Webb et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)
Microfluidic fabrication and characterization of Sorafenib-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery
Nayab Tahir et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)
Global efforts on vaccines for COVID-19: Since, sooner or later, we all will catch the coronavirus
Raju Mukherjee
JOURNAL OF BIOSCIENCES (2020)
Hydrophobic Domain Structure of Linear-Dendritic Poly(ethylene glycol) Lipids Affects RNA Delivery of Lipid Nanoparticles
Kejin Zhou et al.
MOLECULAR PHARMACEUTICS (2020)
Paper-Based Device for the Facile Colorimetric Determination of Lithium Ions in Human Whole Blood
Takeshi Komatsu et al.
ACS SENSORS (2020)
Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing
Qiang Cheng et al.
NATURE NANOTECHNOLOGY (2020)
Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to siRNA Delivery
Niko Kimura et al.
ACS APPLIED MATERIALS & INTERFACES (2020)
Self-Degradable Lipid-Like Materials Based on Hydrolysis accelerated by the intra-Particle Enrichment of Reactant (HyPER) for Messenger RNA Delivery
Hiroki Tanaka et al.
ADVANCED FUNCTIONAL MATERIALS (2020)
In silico design and 3D printing of microfluidic chips for the preparation of size-controllable siRNA nanocomplexes
Yongquan Li et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)
Resveratrol Enhances mRNA and siRNA Lipid Nanoparticles Primary CLL Cell Transfection
Edo Kon et al.
PHARMACEUTICS (2020)
Real-Time Measurement of Protein Crystal Growth Rates within the Microfluidic Device to Understand the Microspace Effect
Masatoshi Maeki et al.
ACS OMEGA (2020)
COVID-19 Vaccine Frontrunners and Their Nanotechnology Design
Young Hun Chung et al.
ACS NANO (2020)
Manufacturing Considerations for the Development of Lipid Nanoparticles Using Microfluidics
Carla B. Roces et al.
PHARMACEUTICS (2020)
Polysarcosine-Functionalized Lipid Nanoparticles for Therapeutic mRNA Delivery
Sara S. Nogueira et al.
ACS APPLIED NANO MATERIALS (2020)
Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles
Jayesh A. Kulkarni et al.
NANOSCALE (2020)
The use of design of experiments with multiple responses to determine optimal formulations for in vivo hepatic mRNA delivery
Akari Hashiba et al.
JOURNAL OF CONTROLLED RELEASE (2020)
CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy
Daniel Rosenblum et al.
SCIENCE ADVANCES (2020)
Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis
Masatoshi Maeki et al.
CHEMICAL SCIENCE (2020)
Electrohydrodynamic-Driven Micromixing for the Synthesis of Highly Monodisperse Nanoscale Liposomes
Paresa Modarres et al.
ACS APPLIED NANO MATERIALS (2020)
Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines
Kimberly J. Hassett et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2019)
Formulation and manufacturing of lymphatic targeting liposomes using microfluidics
Swapnil Khadke et al.
JOURNAL OF CONTROLLED RELEASE (2019)
Recent Progress in Microfluidics-Based Biosensing
Yanling Song et al.
ANALYTICAL CHEMISTRY (2019)
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
Akin Akinc et al.
NATURE NANOTECHNOLOGY (2019)
Single-cell RT-LAMP mRNA detection by integrated droplet sorting and merging
Meng Ting Chung et al.
LAB ON A CHIP (2019)
On the role of helper lipids in lipid nanoparticle formulations of siRNA
Jayesh A. Kulkarni et al.
NANOSCALE (2019)
pPB Peptide-Mediated siRNA-Loaded Stable Nucleic Acid Lipid Nanoparticles on Targeting Therapy of Hepatic Fibrosis
Zongxiang Jia et al.
MOLECULAR PHARMACEUTICS (2018)
On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA
Jayesh A. Kulkarni et al.
ACS NANO (2018)
Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems
Masatoshi Maeki et al.
ADVANCED DRUG DELIVERY REVIEWS (2018)
Ionizable Amino-Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino-Alcohols for Tissue Selective mRNA Delivery
Piotr S. Kowalski et al.
ADVANCED MATERIALS (2018)
A Versatile, Low-Cost, Multiway Microfluidic Sorter for Droplets, Cells, and Embryos
Ramesh Utharala et al.
ANALYTICAL CHEMISTRY (2018)
Evaluation of siRNA and cationic liposomes complexes as a model for in vitro siRNA delivery to cancer cells
Ismail Es et al.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2018)
Wearable sensors: modalities, challenges, and prospects
J. Heikenfeld et al.
LAB ON A CHIP (2018)
A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates
Staci Sabnis et al.
MOLECULAR THERAPY (2018)
mRNA vaccines - a new era in vaccinology
Norbert Pardi et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Effect of Dengue Serostatus on Dengue Vaccine Safety and Efficacy
S. Sridhar et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
Jonathan D. Finn et al.
CELL REPORTS (2018)
Systemic messenger RNA as an etiological treatment for acute intermittent porphyria
Lei Jiang et al.
NATURE MEDICINE (2018)
Development of the iLiNP Device: Fine Tuning the Lipid Nanoparticle Size within 10 nm for Drug Delivery
Niko Kimura et al.
ACS OMEGA (2018)
Paper-Based Microfluidic Devices: Emerging Themes and Applications
Yuanyuan Yang et al.
ANALYTICAL CHEMISTRY (2017)
Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA
Jason B. Miller et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Recent advances in engineering microparticles and their nascent utilization in biomedical delivery and diagnostic applications
Andrew Choi et al.
LAB ON A CHIP (2017)
Progress of crystallization in microfluidic devices
Huan-huan Shi et al.
LAB ON A CHIP (2017)
Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
Kapil Bahl et al.
MOLECULAR THERAPY (2017)
Core/Shell Nanocomposites Produced by Superfast Sequential Microfluidic Nanoprecipitation
Dongfei Liu et al.
NANO LETTERS (2017)
Single-step microfluidic synthesis of transferrin-conjugated lipid nanoparticles for siRNA delivery
Yujing Li et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2017)
Dual-functional lipid-like nanoparticles for delivery of mRNA and MRI contrast agents
X. Luo et al.
NANOSCALE (2017)
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
Hao Yin et al.
NATURE BIOTECHNOLOGY (2017)
Systemic delivery of factor IX messenger RNA for protein replacement therapy
Suvasini Ramaswamy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia
Ding An et al.
CELL REPORTS (2017)
Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers
Masatoshi Maeki et al.
PLOS ONE (2017)
Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes
Owen S. Fenton et al.
ADVANCED MATERIALS (2017)
Biodegradable Amino-Ester Nanomaterials for Cas9 mRNA Delivery in Vitro and in Vivo
Xinfu Zhang et al.
ACS APPLIED MATERIALS & INTERFACES (2017)
Emerging Droplet Microfluidics
Luoran Shang et al.
CHEMICAL REVIEWS (2017)
Modified mRNA Vaccines Protect against Zika Virus Infection
Justin M. Richner et al.
CELL (2017)
A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo
Chao Jiang et al.
CELL RESEARCH (2017)
Core-Shell Chitosan Microcapsules for Programmed Sequential Drug Release
Xiu-Lan Yang et al.
ACS APPLIED MATERIALS & INTERFACES (2016)
Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo
Kevin J. Kauffman et al.
BIOMATERIALS (2016)
Microfluidics based manufacture of liposomes simultaneously entrapping hydrophilic and lipophilic drugs
Sameer Joshi et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)
Elucidation of the physicochemical properties and potency of siRNA-loaded small-sized lipid nanoparticles for siRNA delivery
Yusuke Sato et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA
Sam Chen et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
Hao Yin et al.
NATURE BIOTECHNOLOGY (2016)
A Glu-urea-Lys Ligand-conjugated Lipid Nanoparticle/siRNA System Inhibits Androgen Receptor Expression In Vivo
Justin B Lee et al.
Molecular Therapy-Nucleic Acids (2016)
Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo
Genc Basha et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2016)
Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles
Srinivas Ramishetti et al.
ACS NANO (2015)
Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems
Alex K. K. Leung et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2015)
An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in Vivo
Bin Li et al.
NANO LETTERS (2015)
Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs
Kevin J. Kauffman et al.
NANO LETTERS (2015)
High-Throughput Continuous Flow Production of Nanoscale Liposomes by Microfluidic Vertical Flow Focusing
Renee R. Hood et al.
SMALL (2015)
A strategy for synthesis of lipid nanoparticles using microfluidic devices with a mixer structure
Masatoshi Maeki et al.
RSC ADVANCES (2015)
Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration
Sam Chen et al.
JOURNAL OF CONTROLLED RELEASE (2014)
A facile route to the synthesis of monodisperse nanoscale liposomes using 3D microfluidic hydrodynamic focusing in a concentric capillary array
Renee R. Hood et al.
LAB ON A CHIP (2014)
Non-viral vectors for gene-based therapy
Hao Yin et al.
NATURE REVIEWS GENETICS (2014)
Shielding of Lipid Nanoparticles for siRNA Delivery: Impact on Physicochemical Properties, Cytokine Induction, and Efficacy
Varun Kumar et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2014)
Analysis of Flow and Mixing Characteristics of Planar Asymmetric Split-and-Recombine (P-SAR) Micromixers with Fan-Shaped Cavities
Guodong Xia et al.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2012)
Rapid Discovery of Potent siRNA-Containing Lipid Nanoparticles Enabled by Controlled Microfluidic Formulation
Delai Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Bottom-Up Design and Synthesis of Limit Size Lipid Nanoparticle Systems with Aqueous and Triglyceride Cores Using Millisecond Microfluidic Mixing
Igor V. Zhigaltsev et al.
LANGMUIR (2012)
Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA
Nathan M. Belliveau et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2012)
Microfluidic Mixing and the Formation of Nanoscale Lipid Vesicles
Andreas Jahn et al.
ACS NANO (2010)
Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment
Marc T. Abrams et al.
MOLECULAR THERAPY (2010)
Controlled vesicle self-assembly in microfluidic channels with hydrodynamic focusing
A Jahn et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)