4.7 Review

Inoperable Early-Stage Non-Small-Cell Lung Cancer: Stereotactic Ablative Radiotherapy and Rationale for Systemic Therapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Regulatory T Cells Shape the Differential Impact of Radiation Dose-Fractionation Schedules on Host Innate and Adaptive Antitumor Immune Defenses

Joseph Sia et al.

Summary: The study revealed that radiation dose per fraction and total dose can independently and differentially affect the immunomodulatory capacity of radiation therapy. Radiation dose per fraction had a greater impact on inducing local antitumor T cell responses, while total dose was more influential on natural killer cell-mediated control of irradiated tumors.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2021)

Article Oncology

The HILUS-Trial-a Prospective Nordic Multicenter Phase 2 Study of Ultracentral Lung Tumors Treated With Stereotactic Body Radiotherapy

Karin Lindberg et al.

Summary: This study focused on thoracic tumors located within 1 cm from the proximal bronchial tree and found that the standard treatment of 7 Gy x 8 should be avoided for such tumors. Tumors further away from the main bronchi and trachea may be considered for treatment based on an individual risk-benefit assessment.

JOURNAL OF THORACIC ONCOLOGY (2021)

Article Oncology

Neoadjuvant durvalumab with or without stereotactic body radiotherapy in patients with early-stage non-small-cell lung cancer: a single-centre, randomised phase 2 trial

Nasser K. Altorki et al.

Summary: The combination of neoadjuvant durvalumab and stereotactic body radiotherapy in early-stage NSCLC patients shows a high major pathological response rate and is well tolerated, suggesting its potential in treatment, although it comes with certain adverse events.

LANCET ONCOLOGY (2021)

Article Oncology

ALCHEMIST: Adjuvant targeted therapy or immunotherapy for high-risk resected NSCLC.

Jacob Sands et al.

JOURNAL OF CLINICAL ONCOLOGY (2020)

Article Medicine, General & Internal

Osimertinib in Resected EGFR-Mutated Non-Small-Cell Lung Cancer

Yi-Long Wu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Oncology

Low-dose radiation treatment enhances systemic antitumor immune responses by overcoming the inhibitory stroma

Hampartsoum B. Barsoumian et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

Article Oncology

Chest Wall Toxicity After Stereotactic Body Radiation Therapy: A Pooled Analysis of 57 Studies

Jie-Tao Ma et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2019)

Article Medicine, General & Internal

Neoadjuvant PD-1 Blockade in Resectable Lung Cancer

P. M. Forde et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC

S. J. Antonia et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer

S. J. Antonia et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Stereotactic Body Radiation Therapy for Inoperable Early Stage Lung Cancer

Robert Timmerman et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)

Article Medicine, General & Internal

Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer

T Winton et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Medicine, General & Internal

Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer

T Le Chevalier et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Article Cardiac & Cardiovascular Systems

Stereotactic radiosurgery for lung tumors: Preliminary report of a phase I trial

RI Whyte et al.

ANNALS OF THORACIC SURGERY (2003)