4.7 Article

SARS-CoV-2 in Childhood Cancer in 2020: A Disease of Disparities

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Immunology

COVID-19 in Immunocompromised Hosts: What We Know So Far

Monica Fung et al.

Summary: The COVID-19 pandemic caused by SARS-CoV-2 has led to significant morbidity and mortality globally. The impact of the disease on immunosuppressed patients, such as cancer patients and transplant recipients, remains unclear. Further research is needed to determine the risk of COVID-19 severity and death in immunocompromised patients.

CLINICAL INFECTIOUS DISEASES (2021)

Review Medicine, General & Internal

Racial and Ethnic Disparities in COVID-19-Related Infections, Hospitalizations, and Deaths A Systematic Review

Katherine Mackey et al.

Summary: African American/Black and Hispanic populations in the U.S. have higher rates of SARS-CoV-2 infections, hospitalizations, and COVID-19-related mortality compared to non-Hispanic White populations. However, case fatality rates are similar. Health care access and exposure risks may contribute to the observed disparities.

ANNALS OF INTERNAL MEDICINE (2021)

Article Oncology

Severity of COVID-19 in children with cancer: Report from the United Kingdom Paediatric Coronavirus Cancer Monitoring Project

Gerard C. Millen et al.

Summary: This study aimed to provide evidence on the incidence and outcomes of SARS-CoV-2 in children with cancer attending hospitals in the UK. The study found that children with cancer appear to have similar risk of severe SARS-CoV-2 infection compared to the general pediatric population, with an estimated incidence of 3% in this group. This supports the continued delivery of standard treatment for children with cancer during the pandemic.

BRITISH JOURNAL OF CANCER (2021)

Article Pediatrics

Assessment of 135 794 Pediatric Patients Tested for Severe Acute Respiratory Syndrome Coronavirus 2 Across the United States

L. Charles Bailey et al.

Summary: This cohort study of US pediatric patients found low rates of SARS-CoV-2 infection, with mild clinical manifestations. Infection was associated with Black, Hispanic, and Asian race/ethnicity, adolescence and young adulthood, as well as non-respiratory chronic medical conditions. The study suggests higher concern may be warranted for patients with complex medical conditions or minority race/ethnicity.

JAMA PEDIATRICS (2021)

Article Infectious Diseases

Differences of blood cells, lymphocyte subsets and cytokines in COVID-19 patients with different clinical stages: a network meta-analysis

Wu Yan et al.

Summary: This study found that white blood cell, neutrophil, IL-6, and IL-10 counts increased significantly with worsening of COVID-19, while lymphocyte counts decreased. Platelet, CD3(+), CD4(+), CD8(+), and CD19(+) cell levels in severe and critical patients were significantly lower than those in mild patients. IL-1 beta count was significantly elevated in critical patients, indicating the crucial roles of immune suppression and inflammatory injury in the progression of COVID-19.

BMC INFECTIOUS DISEASES (2021)

Article Immunology

Risk Factors for Severe COVID-19 in Children

Kelly Graff et al.

Summary: This study found that extremes of age, comorbid conditions, and elevated CRP are predictors of severe COVID-19 disease in children. These findings can help pediatric providers and public health officials tailor clinical management and resource allocation strategies more effectively.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2021)

Letter Oncology

COVID-19 in Children With Cancer in New York City

Farid Boulad et al.

JAMA ONCOLOGY (2020)

Article Physiology

Understanding the age divide in COVID-19: why are children overwhelmingly spared?

K. Lingappan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2020)

Editorial Material Cardiac & Cardiovascular Systems

Pulling at the heart: COVID-19, race/ethnicity and ongoing disparities

Peter Chin-Hong et al.

NATURE REVIEWS CARDIOLOGY (2020)

Review Pediatrics

Clinical characteristics of COVID-19 in children: A systematic review

Jun Yasuhara et al.

PEDIATRIC PULMONOLOGY (2020)

Review Infectious Diseases

COVID-19 and multisystem inflammatory syndrome in children and adolescents

Li Jiang et al.

LANCET INFECTIOUS DISEASES (2020)

Editorial Material Oncology

Progress Born From a Legacy of Collaboration

Melissa M. Hudson et al.

JOURNAL OF CLINICAL ONCOLOGY (2015)