4.6 Article

Myricetin inhibits breast and lung cancer cells proliferation via inhibiting MARK4

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Insight into the binding of PEG-400 with eye protein alpha-crystallin: Multi spectroscopic and computational approach: possible therapeutics targeting eye diseases

Anas Shamsi et al.

Summary: This study investigated the binding of alpha-crystallin and PEG-400 using various spectroscopic techniques and molecular modeling. The results suggest a strong binding between alpha-crystallin and PEG-400, driven by van der Waals forces and hydrogen bonding. Molecular docking further confirmed the binding site of PEG-400 in alpha-crystallin.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2022)

Review Nutrition & Dietetics

Polyphenols and Human Health: The Role of Bioavailability

Chiara Di Lorenzo et al.

Summary: Polyphenols are a group of phytochemicals with potential health-promoting effects, classified as flavonoid and non-flavonoid molecules. Their positive effects on health are influenced by factors affecting their bioavailability, and recent studies have shown that their metabolites may have beneficial properties.

NUTRIENTS (2021)

Review Biochemistry & Molecular Biology

Modulation of Autophagy in Cancer Cells by Dietary Polyphenols

Claudia Musial et al.

Summary: The diverse roles of autophagy in cancer development and progression are discussed, highlighting its potential as both a promoter and protector of tumors. The review also emphasizes the increasing use of polyphenols in cancer prevention and treatment, showcasing how these compounds modulate autophagy-induced cancer cell death.

ANTIOXIDANTS (2021)

Article Biochemistry & Molecular Biology

Targeting cyclin-dependent kinase 6 by vanillin inhibits proliferation of breast and lung cancer cells: Combined computational and biochemical studies

Mohd Yousuf et al.

Summary: The study demonstrated the inhibitory potential of vanillin on CDK6, leading to decreased cell viability and colonization properties of cancer cells, indicating its therapeutic implications in anticancer therapies.

JOURNAL OF CELLULAR BIOCHEMISTRY (2021)

Review Biochemistry & Molecular Biology

Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy

Saleha Anwar et al.

Summary: The metabolism of cancer cells is closely related to the inhibition of PDC, which can be targeted as an attractive strategy in anticancer therapy. Research on the PDC/PDK axis may contribute to the therapeutic management of cancer by developing potential small-molecule PDK inhibitors. In recent years, there has been increasing attention from the scientific community in targeting the PDC/PDK axis for cancer treatment.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2021)

Article Biochemistry & Molecular Biology

Structure-based investigation of MARK4 inhibitory potential of Naringenin for therapeutic management of cancer and neurodegenerative diseases

Saleha Anwar et al.

Summary: The study suggests that Naringenin (NAG) may be an effective inhibitor of MARK4, as indicated by molecular docking and MD simulation studies showing that NAG can stabilize the structure of MARK4 and has excellent binding affinity with an impressive IC50 value.

JOURNAL OF CELLULAR BIOCHEMISTRY (2021)

Article Biochemistry & Molecular Biology

Development of grape polyphenols as multi-targeting strategies for Alzheimer's disease

Farida El Gaamouch et al.

Summary: Alzheimer's disease (AD) is a prevalent neurodegenerative disease of aging, posing a major burden for patients, caregivers, and the healthcare system. Due to the complexity of AD pathophysiology and limited treatment options, there is a growing interest in the scientific community in exploring the impact of diet and nutrition on AD. Grape derived polyphenols are considered as potential novel strategies for AD treatment, showing promising results in modulating various aspects of AD pathophysiology.

NEUROCHEMISTRY INTERNATIONAL (2021)

Article Biochemistry & Molecular Biology

Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6

Mohd Yousuf et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Chemistry, Physical

Understanding the binding between Rosmarinic acid and serum albumin: In vitro and in silico insight

Anas Shamsi et al.

JOURNAL OF MOLECULAR LIQUIDS (2020)

Article Multidisciplinary Sciences

Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition

Saleha Anwar et al.

SCIENTIFIC REPORTS (2020)

Article Biochemistry & Molecular Biology

Structural and biochemical investigation of MARK4 inhibitory potential of cholic acid: Towards therapeutic implications in neurodegenerative diseases

Saleha Anwar et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Medicine, Research & Experimental

Evaluation of ellagic acid as an inhibitor of sphingosine kinase 1: A targeted approach towards anticancer therapy

Preeti Gupta et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

Article Biochemistry & Molecular Biology

Probing the interaction of anticancer drug temsirolimus with human serum albumin: molecular docking and spectroscopic insight

Anas Shamsi et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2018)

Article Biochemistry & Molecular Biology

Biological evaluation of p-toluene sulphonylhydrazone as carbonic anhydrase IX inhibitors: An approach to fight hypoxia-induced tumors

Aarfa Queen et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Chemistry, Medicinal

GPU-Accelerated Molecular Dynamics and Free Energy Methods in Amber18: Performance Enhancements and New Features

Tai-Sung Lee et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2018)

Review Agronomy

Polyphenols and brain health

David Vauzour

OCL-OILSEEDS AND FATS CROPS AND LIPIDS (2017)

Article Biochemistry & Molecular Biology

MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells

Emad Heidary Arash et al.

EMBO REPORTS (2017)

Article Biochemistry & Molecular Biology

miR-515-5p controls cancer cell migration through MARK4 regulation

Olivier E. Pardo et al.

EMBO REPORTS (2016)

Article Biochemistry & Molecular Biology

Ubiquitin-associated domain of MARK4 provides stability at physiological pH

Farha Naz et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)

Review Nutrition & Dietetics

Myricetin: A Dietary Molecule with Diverse Biological Activities

Deepak Kumar Semwal et al.

NUTRIENTS (2016)

Article Biochemical Research Methods

Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor

John S. Sack et al.

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2016)

Review Biochemistry & Molecular Biology

9 Chitinase from Thermomyces lanuginosus SSBP and its biotechnological applications

Faez Iqbal Khan et al.

EXTREMOPHILES (2015)

Article Chemistry, Physical

Grid-Based Backbone Correction to the ff12SB Protein Force Field for Implicit-Solvent Simulations

Alberto Perez et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)

Review Biochemistry & Molecular Biology

A Review of Methods Available to Estimate Solvent-Accessible Surface Areas of Soluble Proteins in the Folded and Unfolded States

Syed Ausaf Ali et al.

CURRENT PROTEIN & PEPTIDE SCIENCE (2014)

Software Review Chemistry, Medicinal

Origin Pro 9.1: Scientific Data Analysis and Graphing Software-Software Review

E. Seifert

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2014)

Article Medicine, Research & Experimental

Insight into the Binding Mechanism of Imipenem to Human Serum Albumin by Spectroscopic and Computational Approaches

Md Tabish Rehman et al.

MOLECULAR PHARMACEUTICS (2014)

Article Chemistry, Physical

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

Daniel R. Roe et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)

Article Biochemistry & Molecular Biology

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

G. Madhavi Sastry et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2013)

Article Biochemistry & Molecular Biology

Phenotypic Characterization of the Binding of Tetracycline to Human Serum Albumin

Zhenxing Chi et al.

BIOMACROMOLECULES (2011)

Review Nutrition & Dietetics

Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action

David Vauzour et al.

NUTRIENTS (2010)

Review Oncology

Functional proteomics to dissect tyrosine kinase signalling pathways in cancer

Walter Kolch et al.

NATURE REVIEWS CANCER (2010)

Review Physiology

The regulation and function of mammalian AMPK-related kinases

N. J. Bright et al.

ACTA PHYSIOLOGICA (2009)

Article Pharmacology & Pharmacy

Interaction of mitoxantrone with human serum albumin: Spectroscopic and molecular modeling studies

Shahper N. Khan et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2008)

Article Agriculture, Multidisciplinary

Interaction of different polyphenols with bovine serum albumin (BSA) and human salivary α-amylase (HSA) by fluorescence quenching

Susana Soares et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2007)

Article Biochemical Research Methods

Automatic atom type and bond type perception in molecular mechanical calculations

Junmei Wang et al.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2006)

Article Chemistry, Medicinal

Glide: A new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

RA Friesner et al.

JOURNAL OF MEDICINAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Interactions between PAMAM dendrimers and bovine serum albumin

B Klajnert et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2003)

Article Multidisciplinary Sciences

The protein kinase complement of the human genome

G Manning et al.

SCIENCE (2002)

Article Biochemistry & Molecular Biology

Role of Arg-410 and Tyr-411 in human serum albumin for ligand binding and esterase-like activity

H Watanabe et al.

BIOCHEMICAL JOURNAL (2000)

Review Biochemistry & Molecular Biology

PARsing embryonic polarity

K Kemphues