4.7 Article

LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

CEP55 promotes cilia disassembly through stabilizing Aurora A kinase

Yu-Cheng Zhang et al.

Summary: Primary cilia protruding from the cell surface play important roles in development and disease. CEP55 has been identified as a key regulator in cilia disassembly, with CEP55 deficiency causing manifestations of Meckel-Gruber syndrome and abnormal cilia elongation in tissues.

JOURNAL OF CELL BIOLOGY (2021)

Review Cell Biology

Emerging functions of branched ubiquitin chains

Michael E. French et al.

Summary: Ubiquitylation is a critical post-translational modification that controls various cellular processes. Different topologies of ubiquitin chains regulate the stability, activity, interaction properties, and localization of proteins. Recent studies have shown that branched ubiquitin chains play a role in cell signaling and protein degradation pathways, with diverse chemical linkages and structures.

CELL DISCOVERY (2021)

Article Multidisciplinary Sciences

LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis

Huai-Bin Hu et al.

Summary: Dynamic assembly and disassembly of primary cilia play critical roles in tissue development and homeostasis. The authors have identified lysophosphatidic acid (LPA) as a physiological extracellular factor that initiates cilia disassembly through both YAP/TAZ mediated transcription and calcium/calmodulin mediated activation of Aurora A.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin

Yesheng Fu et al.

Summary: The study demonstrates that OTULIN and LUBAC cooperatively regulate ALK1 activity to balance endothelial cell angiogenesis, which is crucial for the development of arteriovenous malformations and other related diseases.

MOLECULAR CELL (2021)

Article Biology

CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

Andre Bras Goncalves et al.

Summary: CEP78 is a centrosomal protein involved in ciliogenesis and ciliary length control. Through interaction with other proteins like CEP350 and EDD1, CEP78 negatively regulates CP110 level to promote ciliogenesis downstream of CEP350. This discovery provides important insights into the role of CEP78 in cellular ciliogenesis.
Article Multidisciplinary Sciences

Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling

Yibo Zuo et al.

NATURE COMMUNICATIONS (2020)

Article Cell Biology

Rab7 regulates primary cilia disassembly through cilia excision

Guang Wang et al.

JOURNAL OF CELL BIOLOGY (2019)

Article Multidisciplinary Sciences

LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores

Min Wu et al.

NATURE COMMUNICATIONS (2019)

Article Cell Biology

The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia

Robert F. Shearer et al.

MOLECULAR BIOLOGY OF THE CELL (2018)

Article Multidisciplinary Sciences

Myosin1D is an evolutionarily conserved regulator of animal left-right asymmetry

Thomas Juan et al.

NATURE COMMUNICATIONS (2018)

Article Cell Biology

Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation

Tomoaki Nagai et al.

JOURNAL OF CELL SCIENCE (2018)

Article Cell Biology

TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation

Elodie Lafont et al.

NATURE CELL BIOLOGY (2018)

Article Multidisciplinary Sciences

Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis

Hai-Qing Tu et al.

NATURE COMMUNICATIONS (2018)

Article Medicine, General & Internal

Polycystic kidney disease

Carsten Bergmann et al.

NATURE REVIEWS DISEASE PRIMERS (2018)

Article Cell Biology

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones

Anna Malinova et al.

JOURNAL OF CELL BIOLOGY (2017)

Article Cell Biology

The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome

Abdelhalim Loukil et al.

JOURNAL OF CELL BIOLOGY (2017)

Article Genetics & Heredity

Guidelines for morpholino use in zebrafish

Didier Y. R. Stainier et al.

PLOS GENETICS (2017)

Article Biochemistry & Molecular Biology

Cep78 controls centrosome homeostasis by inhibiting EDD-DYRK2-DDB1VprBP

Delowar Hossain et al.

EMBO REPORTS (2017)

Review Cell Biology

Cilium assembly and disassembly

Irma Sanchez et al.

NATURE CELL BIOLOGY (2016)

Review Cell Biology

The increasing complexity of the ubiquitin code

Richard Yau et al.

NATURE CELL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Myosin heavy chain 10 (MYH10) is required for centriole migration during the biogenesis of primary cilia

Hyowon Hong et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Review Immunology

Linear ubiquitination signals in adaptive immune responses

Fumiyo Ikeda

IMMUNOLOGICAL REVIEWS (2015)

Article Cell Biology

Centrin2 regulates CP110 removal in primary cilium formation

Suzanna L. Prosser et al.

JOURNAL OF CELL BIOLOGY (2015)

Article Immunology

The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation

Mary A. Rodgers et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2014)

Review Cell Biology

Linear ubiquitin chains: NF-κB signalling, cell death and beyond

Kazuhiro Iwai et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin

Kirstin Keusekotten et al.

Article Cell Biology

Assembling a primary cilium

Sehyun Kim et al.

CURRENT OPINION IN CELL BIOLOGY (2013)

Article Multidisciplinary Sciences

The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis

Elena Rivkin et al.

NATURE (2013)

Article Multidisciplinary Sciences

CCDC41 is required for ciliary vesicle docking to the mother centriole

Kwangsic Joo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

Christoph H. Emmerich et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Biochemistry & Molecular Biology

The Ubiquitin Code

David Komander et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)

Article Biochemistry & Molecular Biology

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

Benjamin Stieglitz et al.

EMBO REPORTS (2012)

Article Biochemistry & Molecular Biology

Engineering and Structural Characterization of a Linear Polyubiquitin-Specific Antibody

Marissa L. Matsumoto et al.

JOURNAL OF MOLECULAR BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Centriolar Kinesin Kif24 Interacts with CP110 to Remodel Microtubules and Regulate Ciliogenesis

Tetsuo Kobayashi et al.

Article Biochemistry & Molecular Biology

Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

Liyun Sang et al.

Article Multidisciplinary Sciences

Linear ubiquitination prevents inflammation and regulates immune signalling

Bjoern Gerlach et al.

NATURE (2011)

Article Genetics & Heredity

A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition

Francesc R. Garcia-Gonzalo et al.

NATURE GENETICS (2011)

Article Genetics & Heredity

Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes

Enza Maria Valente et al.

NATURE GENETICS (2010)

Review Biochemistry & Molecular Biology

Centrioles, Centrosomes, and Cilia in Health and Disease

Erich A. Nigg et al.

Review Biochemistry & Molecular Biology

The Vertebrate Primary Cilium in Development, Homeostasis, and Disease

Jantje M. Gerdes et al.

Article Biochemistry & Molecular Biology

Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation

Simin Rahighi et al.

Review Biochemistry & Molecular Biology

Linear polyubiquitination: a new regulator of NF-κB activation

Kazuhiro Iwai et al.

EMBO REPORTS (2009)

Review Medicine, Research & Experimental

Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy

Norann A. Zaghloul et al.

JOURNAL OF CLINICAL INVESTIGATION (2009)

Article Cell Biology

Involvement of linear polyubiquitylation of NEMO in NF-κB activation

Fuminori Tokunaga et al.

NATURE CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis

Sunny Y. Wong et al.

NATURE MEDICINE (2009)

Article Cell Biology

Double life of centrioles: CP110 in the spotlight

Monica Bettencourt-Dias et al.

TRENDS IN CELL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Cep97 and CP110 suppress a cilia assembly program

Alexander Spektor et al.

Article Multidisciplinary Sciences

Patched1 regulates Hedgehog signaling at the primary cilium

Rajat Rohatgi et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

A ubiquitin ligase complex assembles linear polyubiquitin chains

Takayoshi Kirisako et al.

EMBO JOURNAL (2006)

Review Multidisciplinary Sciences

The primary cilium as the cell's antenna: Signaling at a sensory organelle

Veena Singla et al.

SCIENCE (2006)

Review Biochemistry & Molecular Biology

Ubiquitylation and cell signaling

K Haglund et al.

EMBO JOURNAL (2005)

Review Biochemistry & Molecular Biology

Prp8 protein: At the heart of the spliceosome

RJ Grainger et al.

Article Biochemistry & Molecular Biology

Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13)

AB McKie et al.

HUMAN MOLECULAR GENETICS (2001)

Review Biochemistry & Molecular Biology

Mechanisms of left-right determination in vertebrates

J Capdevila et al.