4.4 Review

C4-Dicarboxylates as Growth Substrates and Signaling Molecules for Commensal and Pathogenic Enteric Bacteria in Mammalian Intestine

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

L-Aspartate as a high-quality nitrogen source in Escherichia coli: Regulation of L-aspartase by the nitrogen regulatory system and interaction of L-aspartase with GlnB

Christopher Schubert et al.

Summary: Escherichia coli uses the C4-dicarboxylate transporter DcuA to transport L-aspartate and fumarate, facilitating nitrogen assimilation under various oxygen conditions. The central regulator GlnB interacts with AspA to stimulate its activity in releasing ammonia for the synthesis of amino acids. This process integrates AspA into the nitrogen assimilation network in E. coli.

MOLECULAR MICROBIOLOGY (2021)

Article Multidisciplinary Sciences

Host succinate is an activation signal for Salmonella virulence during intracellular infection

Gili Rosenberg et al.

Summary: The translation discusses the importance of intracellular pathogens sensing and responding to changing host cell environments, and how Salmonella Typhimurium utilizes succinate accumulation in macrophages to enhance its antimicrobial resistance and virulence.

SCIENCE (2021)

Article Microbiology

C4-dicarboxylates and l-aspartate utilization by Escherichia coli K-12 in the mouse intestine: l-aspartate as a major substrate for fumarate respiration and as a nitrogen source

Christopher Schubert et al.

Summary: The study found that C4-dicarboxylates and fumarate respiration play important roles in the colonization of the mammalian intestinal tract by Escherichia coli, with L-aspartate being crucial for providing fumarate and nitrogen for bacterial growth in the mouse intestine. Mutants with defective anaerobic C4-dicarboxylate metabolism were impaired in colonizing the murine gut.

ENVIRONMENTAL MICROBIOLOGY (2021)

Article Biology

Reshaping of bacterial molecular hydrogen metabolism contributes to the outgrowth of commensal E. coli during gut inflammation

Elizabeth R. Hughes et al.

Summary: During intestinal inflammation, the composition of gut-associated microbial communities changes, with an increase in Enterobacteriaceae populations. The analysis of microbial hydrogen metabolism revealed that bacterial genomes in the inflamed gut contained more genes encoding predicted hydrogen-utilizing hydrogenases. E. coli mutants lacking hydrogenase-1 and hydrogenase-2 displayed decreased fitness during colonization of the inflamed gut, suggesting the importance of hydrogenases in the context of non-infectious colitis.
Article Biochemical Research Methods

Fumarate dependent protein composition under aerobic and anaerobic growth conditions in Escherichia coli

Kristin Surmann et al.

JOURNAL OF PROTEOMICS (2020)

Article Endocrinology & Metabolism

Gut microbiota-derived succinate: Friend or foe in human metabolic diseases?

Sonia Fernandez-Veledo et al.

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2019)

Review Nutrition & Dietetics

Probiotics, prebiotics, synbiotics and insulin sensitivity

Y. A. Kim et al.

NUTRITION RESEARCH REVIEWS (2018)

Article Biochemistry & Molecular Biology

DcuA of aerobically grown Escherichia coli serves as a nitrogen shuttle (L-aspartate/fumarate) for nitrogen uptake

Alexander Strecker et al.

MOLECULAR MICROBIOLOGY (2018)

Review Biochemistry & Molecular Biology

Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers

Michael P. Murphy et al.

Article Multidisciplinary Sciences

Accumulation of succinate controls activation of adipose tissue thermogenesis

Evanna L. Mills et al.

NATURE (2018)

Article Gastroenterology & Hepatology

Functional Characterization of Inflammatory Bowel Disease-Associate Gut Dysbiosis in Gnotobiotic Mice

Hiroko Nagao-Kitamoto et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2016)

Article Multidisciplinary Sciences

Transmembrane signaling in the sensor kinase DcuS of Escherichia coli: A long-range piston-type displacement of transmembrane helix 2

Christian Monzel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

Edward T. Chouchani et al.

NATURE (2014)

Article Cell Biology

Identifying Gut Microbe-Host Phenotype Relationships Using Combinatorial Communities in Gnotobiotic Mice

Jeremiah J. Faith et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Article Genetics & Heredity

Determining the Control Circuitry of Redox Metabolism at the Genome-Scale

Stephen Federowicz et al.

PLOS GENETICS (2014)

Article Multidisciplinary Sciences

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

G. M. Tannahill et al.

NATURE (2013)

Review Microbiology

Nitrogen Assimilation in Escherichia coli: Putting Molecular Data into a Systems Perspective

Wally C. van Heeswijk et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2013)

Article Multidisciplinary Sciences

Host-Derived Nitrate Boosts Growth of E. coli in the Inflamed Gut

Sebastian E. Winter et al.

SCIENCE (2013)

Review Microbiology

PII signal transduction proteins: nitrogen regulation and beyond

Luciano F. Huergo et al.

FEMS MICROBIOLOGY REVIEWS (2013)

Article Immunology

Anaerobic Respiration of Escherichia coli in the Mouse Intestine

Shari A. Jones et al.

INFECTION AND IMMUNITY (2011)

Article Multidisciplinary Sciences

Gut inflammation provides a respiratory electron acceptor for Salmonella

Sebastian E. Winter et al.

NATURE (2010)

Article Biochemistry & Molecular Biology

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

Bryson D. Bennett et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Immunology

Respiration of Escherichia coli in the mouse intestine

Shari A. Jones et al.

INFECTION AND IMMUNITY (2007)

Review Biotechnology & Applied Microbiology

Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

Csaba Szabo et al.

NATURE REVIEWS DRUG DISCOVERY (2007)

Review Microbiology

How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteria

Josef Deutscher et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2006)

Article Biochemistry & Molecular Biology

A global regulatory role of gluconeogenic genes in Escherichia coli revealed by transcriptome network analysis

KC Kao et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

The nature of the stimulus and of the fumarate binding site of the fumarate sensor DcuS of Escherichia coli

H Kneuper et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

Transcriptome-based determination of multiple transcription regulator activities in Escherichia coli by using network component analysis

KC Kao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Multidisciplinary Sciences

Carbon nutrition of Escherichia coli in the mouse intestine

DE Chang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Global expression profiling of acetate-grown Escherichia coli

MK Oh et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Review Biochemistry & Molecular Biology

Fumarate respiration of Wolinella succinogenes:: enzymology, energetics and coupling mechanism

A Kröger et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2002)