Two new flavonol glycosides from Selaginella tamariscina

Two new flavonol glycosides 3,5,7-trimethoxyflavone-4'-O-[5'''-O-p-coumaroyl-beta-D-apiofuranoyl-(1'''-> 2'')-beta-D-glucopyranoside] (1) and 3,5,7-trimethoxyflavone -4'-O-beta-D-glucopyranoside (2) were isolated from Selaginella tamariscina. The structures of 1 and 2 were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HRESIMS spectrometry. Two compounds were evaluated for cytotoxic activities against A-375, MCF-7, MDA-MB-231 and MDA-MB-468 cell lines by MTT assay. Unfortunately, two compounds displayed no cytotoxic activities.

Automated summary

Two new flavonol glycosides were isolated from Selaginella tamariscina, but showed no cytotoxic activities against four different cell lines.